node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Veis_0081 | Veis_0082 | Veis_0081 | Veis_0082 | KEGG: pol:Bpro_2609 hypothetical protein. | KEGG: pol:Bpro_2610 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | 0.888 |
Veis_0081 | Veis_0085 | Veis_0081 | Veis_0085 | KEGG: pol:Bpro_2609 hypothetical protein. | PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: rfr:Rfer_2312 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family. | 0.496 |
Veis_0081 | der | Veis_0081 | Veis_0076 | KEGG: pol:Bpro_2609 hypothetical protein. | Small GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.811 |
Veis_0081 | ispG | Veis_0081 | Veis_0080 | KEGG: pol:Bpro_2609 hypothetical protein. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.918 |
Veis_0081 | ndk | Veis_0081 | Veis_0084 | KEGG: pol:Bpro_2609 hypothetical protein. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.612 |
Veis_0081 | rlmN | Veis_0081 | Veis_0083 | KEGG: pol:Bpro_2609 hypothetical protein. | Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.656 |
Veis_0082 | Veis_0081 | Veis_0082 | Veis_0081 | KEGG: pol:Bpro_2610 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | KEGG: pol:Bpro_2609 hypothetical protein. | 0.888 |
Veis_0082 | der | Veis_0082 | Veis_0076 | KEGG: pol:Bpro_2610 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | Small GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.767 |
Veis_0082 | ispG | Veis_0082 | Veis_0080 | KEGG: pol:Bpro_2610 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.808 |
Veis_0082 | ndk | Veis_0082 | Veis_0084 | KEGG: pol:Bpro_2610 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.571 |
Veis_0082 | rlmN | Veis_0082 | Veis_0083 | KEGG: pol:Bpro_2610 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.675 |
Veis_0085 | Veis_0081 | Veis_0085 | Veis_0081 | PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: rfr:Rfer_2312 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family. | KEGG: pol:Bpro_2609 hypothetical protein. | 0.496 |
Veis_0085 | der | Veis_0085 | Veis_0076 | PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: rfr:Rfer_2312 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family. | Small GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.853 |
Veis_0085 | ndk | Veis_0085 | Veis_0084 | PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: rfr:Rfer_2312 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.659 |
Veis_0085 | rlmN | Veis_0085 | Veis_0083 | PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: rfr:Rfer_2312 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family. | Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.758 |
Veis_1687 | Veis_4155 | Veis_1687 | Veis_4155 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.563 |
Veis_1687 | miaB | Veis_1687 | Veis_1721 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.456 |
Veis_1687 | rlmN | Veis_1687 | Veis_0083 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.636 |
Veis_4155 | Veis_1687 | Veis_4155 | Veis_1687 | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.563 |
Veis_4155 | miaB | Veis_4155 | Veis_1721 | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.610 |