node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Swoo_1406 | Swoo_1407 | Swoo_1406 | Swoo_1407 | PFAM: Hydratase/decarboxylase; KEGG: swi:Swit_0912 4-oxalocrotonate decarboxylase. | Aminocarboxymuconate-semialdehyde decarboxylase; PFAM: amidohydrolase 2; KEGG: aba:Acid345_0682 tryptophan 2,3-dioxygenase. | 0.802 |
Swoo_1406 | Swoo_1409 | Swoo_1406 | Swoo_1409 | PFAM: Hydratase/decarboxylase; KEGG: swi:Swit_0912 4-oxalocrotonate decarboxylase. | PFAM: Endoribonuclease L-PSP; KEGG: reu:Reut_B5501 endoribonuclease L-PSP. | 0.753 |
Swoo_1406 | kmo | Swoo_1406 | Swoo_1404 | PFAM: Hydratase/decarboxylase; KEGG: swi:Swit_0912 4-oxalocrotonate decarboxylase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.785 |
Swoo_1406 | kynA | Swoo_1406 | Swoo_1403 | PFAM: Hydratase/decarboxylase; KEGG: swi:Swit_0912 4-oxalocrotonate decarboxylase. | Tryptophan 23-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.778 |
Swoo_1406 | kynU | Swoo_1406 | Swoo_1405 | PFAM: Hydratase/decarboxylase; KEGG: swi:Swit_0912 4-oxalocrotonate decarboxylase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.787 |
Swoo_1406 | nbaC | Swoo_1406 | Swoo_1408 | PFAM: Hydratase/decarboxylase; KEGG: swi:Swit_0912 4-oxalocrotonate decarboxylase. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. | 0.699 |
Swoo_1407 | Swoo_1406 | Swoo_1407 | Swoo_1406 | Aminocarboxymuconate-semialdehyde decarboxylase; PFAM: amidohydrolase 2; KEGG: aba:Acid345_0682 tryptophan 2,3-dioxygenase. | PFAM: Hydratase/decarboxylase; KEGG: swi:Swit_0912 4-oxalocrotonate decarboxylase. | 0.802 |
Swoo_1407 | Swoo_1409 | Swoo_1407 | Swoo_1409 | Aminocarboxymuconate-semialdehyde decarboxylase; PFAM: amidohydrolase 2; KEGG: aba:Acid345_0682 tryptophan 2,3-dioxygenase. | PFAM: Endoribonuclease L-PSP; KEGG: reu:Reut_B5501 endoribonuclease L-PSP. | 0.842 |
Swoo_1407 | kmo | Swoo_1407 | Swoo_1404 | Aminocarboxymuconate-semialdehyde decarboxylase; PFAM: amidohydrolase 2; KEGG: aba:Acid345_0682 tryptophan 2,3-dioxygenase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.902 |
Swoo_1407 | kynA | Swoo_1407 | Swoo_1403 | Aminocarboxymuconate-semialdehyde decarboxylase; PFAM: amidohydrolase 2; KEGG: aba:Acid345_0682 tryptophan 2,3-dioxygenase. | Tryptophan 23-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.752 |
Swoo_1407 | kynU | Swoo_1407 | Swoo_1405 | Aminocarboxymuconate-semialdehyde decarboxylase; PFAM: amidohydrolase 2; KEGG: aba:Acid345_0682 tryptophan 2,3-dioxygenase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.922 |
Swoo_1407 | nbaC | Swoo_1407 | Swoo_1408 | Aminocarboxymuconate-semialdehyde decarboxylase; PFAM: amidohydrolase 2; KEGG: aba:Acid345_0682 tryptophan 2,3-dioxygenase. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. | 0.995 |
Swoo_1409 | Swoo_1406 | Swoo_1409 | Swoo_1406 | PFAM: Endoribonuclease L-PSP; KEGG: reu:Reut_B5501 endoribonuclease L-PSP. | PFAM: Hydratase/decarboxylase; KEGG: swi:Swit_0912 4-oxalocrotonate decarboxylase. | 0.753 |
Swoo_1409 | Swoo_1407 | Swoo_1409 | Swoo_1407 | PFAM: Endoribonuclease L-PSP; KEGG: reu:Reut_B5501 endoribonuclease L-PSP. | Aminocarboxymuconate-semialdehyde decarboxylase; PFAM: amidohydrolase 2; KEGG: aba:Acid345_0682 tryptophan 2,3-dioxygenase. | 0.842 |
Swoo_1409 | kmo | Swoo_1409 | Swoo_1404 | PFAM: Endoribonuclease L-PSP; KEGG: reu:Reut_B5501 endoribonuclease L-PSP. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.664 |
Swoo_1409 | kynA | Swoo_1409 | Swoo_1403 | PFAM: Endoribonuclease L-PSP; KEGG: reu:Reut_B5501 endoribonuclease L-PSP. | Tryptophan 23-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.427 |
Swoo_1409 | kynU | Swoo_1409 | Swoo_1405 | PFAM: Endoribonuclease L-PSP; KEGG: reu:Reut_B5501 endoribonuclease L-PSP. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.630 |
Swoo_1409 | nbaC | Swoo_1409 | Swoo_1408 | PFAM: Endoribonuclease L-PSP; KEGG: reu:Reut_B5501 endoribonuclease L-PSP. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. | 0.852 |
Swoo_3394 | Swoo_3881 | Swoo_3394 | Swoo_3881 | PFAM: Catalase domain protein; KEGG: sse:Ssed_3251 catalase; Belongs to the catalase family. | PFAM: Catalase domain protein; KEGG: neu:NE1886 catalase; Belongs to the catalase family. | 0.908 |
Swoo_3394 | Swoo_4923 | Swoo_3394 | Swoo_4923 | PFAM: Catalase domain protein; KEGG: sse:Ssed_3251 catalase; Belongs to the catalase family. | Catalase domain protein; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. | 0.918 |