node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Swoo_0482 | Swoo_0518 | Swoo_0482 | Swoo_0518 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sse:Ssed_4105 porphobilinogen synthase; Belongs to the ALAD family. | 0.874 |
Swoo_0482 | Swoo_0787 | Swoo_0482 | Swoo_0787 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sse:Ssed_3797 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.932 |
Swoo_0482 | Swoo_1872 | Swoo_0482 | Swoo_1872 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sse:Ssed_2768 uroporphyrin-III C-methyltransferase. | 0.923 |
Swoo_0482 | hemA | Swoo_0482 | Swoo_3686 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.690 |
Swoo_0482 | hemC | Swoo_0482 | Swoo_0483 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.998 |
Swoo_0482 | hemE | Swoo_0482 | Swoo_0287 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.942 |
Swoo_0482 | hemL | Swoo_0482 | Swoo_1171 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: sse:Ssed_1088 glutamate-1-semialdehyde-2,1-aminomutase. | 0.551 |
Swoo_0518 | Swoo_0482 | Swoo_0518 | Swoo_0482 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sse:Ssed_4105 porphobilinogen synthase; Belongs to the ALAD family. | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.874 |
Swoo_0518 | Swoo_0787 | Swoo_0518 | Swoo_0787 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sse:Ssed_4105 porphobilinogen synthase; Belongs to the ALAD family. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sse:Ssed_3797 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.880 |
Swoo_0518 | Swoo_1872 | Swoo_0518 | Swoo_1872 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sse:Ssed_4105 porphobilinogen synthase; Belongs to the ALAD family. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sse:Ssed_2768 uroporphyrin-III C-methyltransferase. | 0.880 |
Swoo_0518 | gltX | Swoo_0518 | Swoo_1728 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sse:Ssed_4105 porphobilinogen synthase; Belongs to the ALAD family. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | 0.422 |
Swoo_0518 | hemA | Swoo_0518 | Swoo_3686 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sse:Ssed_4105 porphobilinogen synthase; Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.885 |
Swoo_0518 | hemC | Swoo_0518 | Swoo_0483 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sse:Ssed_4105 porphobilinogen synthase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.996 |
Swoo_0518 | hemE | Swoo_0518 | Swoo_0287 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sse:Ssed_4105 porphobilinogen synthase; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.764 |
Swoo_0518 | hemL | Swoo_0518 | Swoo_1171 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sse:Ssed_4105 porphobilinogen synthase; Belongs to the ALAD family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: sse:Ssed_1088 glutamate-1-semialdehyde-2,1-aminomutase. | 0.993 |
Swoo_0787 | Swoo_0482 | Swoo_0787 | Swoo_0482 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sse:Ssed_3797 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.932 |
Swoo_0787 | Swoo_0518 | Swoo_0787 | Swoo_0518 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sse:Ssed_3797 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sse:Ssed_4105 porphobilinogen synthase; Belongs to the ALAD family. | 0.880 |
Swoo_0787 | Swoo_1872 | Swoo_0787 | Swoo_1872 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sse:Ssed_3797 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sse:Ssed_2768 uroporphyrin-III C-methyltransferase. | 0.910 |
Swoo_0787 | hemA | Swoo_0787 | Swoo_3686 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sse:Ssed_3797 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.797 |
Swoo_0787 | hemC | Swoo_0787 | Swoo_0483 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sse:Ssed_3797 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.988 |