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hpnD protein (Sinorhizobium fredii NGR234) - STRING interaction network
"hpnD" - Presqualene diphosphate synthase in Sinorhizobium fredii NGR234
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hpnDPresqualene diphosphate synthase; Involved in the biosynthesis of the hopanoid precursor squalene (SQ) from farnesyl diphosphate (FPP). Catalyzes the first step, the formation of presqualene diphosphate (PSPP) from two molecules of FPP (279 aa)    
Predicted Functional Partners:
NGR_a00430
Hydroxysqualene synthase; Involved in the biosynthesis of the hopanoid precursor squalene (SQ) from farnesyl diphosphate (FPP). Catalyzes the second step, the conversion of presqualene diphosphate (PSPP) to hydroxysqualene (HSQ) (292 aa)
          0.994
NGR_a00450
Hydroxysqualene dehydroxylase; Involved in the biosynthesis of the hopanoid precursor squalene (SQ) from farnesyl diphosphate (FPP). Catalyzes the third (last) step, the reduction of hydroxysqualene (HSQ) to SQ (417 aa)
   
  0.993
shc
Probable squalene--hopene cyclase; Catalyzes the cyclization of squalene into hopene. Probably part of an operon y4aABCD involved in the synthesis of an isoprenoid compound; Belongs to the terpene cyclase/mutase family (647 aa)
 
   
  0.955
NGR_c32770
annotation not available (360 aa)
   
 
  0.665
ispA
Probable farnesyl diphosphate synthase; y4kU; NGR234_208 (332 aa)
 
 
  0.540
NGR_c15060
annotation not available (301 aa)
   
 
  0.504
ispB
annotation not available (338 aa)
   
 
  0.426
thrB
annotation not available (326 aa)
 
          0.419
lytB
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis; Belongs to the IspH family (336 aa)
   
   
  0.400
Your Current Organism:
Sinorhizobium fredii NGR234
NCBI taxonomy Id: 394
Other names: Ensifer fredii NGR234, Plasmid pNGR234a, Rhizobium sp. (strain NGR234), Rhizobium sp. NGR234, S. fredii NGR234, Sinorhizobium fredii NGR234, Sinorhizobium sp. NGR234
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