STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nifENitrogenase iron-molybdenum cofactor biosynthesis protein NifE; This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor) (496 aa)    
Predicted Functional Partners:
nifN
Nitrogenase iron-molybdenum cofactor biosynthesis protein NifN; This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor)
 
 
 0.999
nifX
nifX; NGR234_418; Belongs to the NifX/NifY family
 
   
 0.991
nifH1
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein
 
 
 0.963
NGR_a01070
UPF0460 protein y4vQ; Similar to y4xD; y4vQ; NGR234_419; Belongs to the UPF0460 family
 
     0.962
nifK1
Nitrogenase molybdenum-iron protein beta chain; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation
   
 0.949
nifB
FeMo cofactor biosynthesis protein NifB; Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster
 
   
 0.941
nifH2
nifH; NGR234_438
 
 
 0.920
nifZ
Putative NifZ protein; nifZ; NGR234_396; Belongs to the NifZ family
 
   
 0.870
nifW
Nitrogenase-stabilizing/protective protein NifW; May protect the nitrogenase Fe-Mo protein from oxidative damage
 
   
 0.864
nifQ
Protein NifQ homolog; Probably involved in molybdenum processing
 
   
 0.849
Your Current Organism:
Sinorhizobium fredii NGR234
NCBI taxonomy Id: 394
Other names: Ensifer fredii NGR234, Plasmid pNGR234a, Rhizobium sp. (strain NGR234), Rhizobium sp. NGR234, S. fredii NGR234, Sinorhizobium fredii NGR234, Sinorhizobium sp. NGR234
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