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ilvC protein (Sinorhizobium fredii NGR234) - STRING interaction network
"ilvC" - Ketol-acid reductoisomerase in Sinorhizobium fredii NGR234
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ilvCKetol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate; Belongs to the ketol-acid reductoisomerase family (339 aa)    
Predicted Functional Partners:
ilvD1
annotation not available (612 aa)
 
  0.996
ilvH
annotation not available (190 aa)
 
  0.992
ilvI
annotation not available (592 aa)
 
 
  0.989
ilvD3
Dihydroxy-acid dehydratase; DAD; Belongs to the IlvD/Edd family (608 aa)
 
  0.985
NGR_c04330
annotation not available (574 aa)
 
  0.985
NGR_c26400
annotation not available (578 aa)
 
  0.984
ilvD2
annotation not available (580 aa)
 
  0.984
NGR_c01990
annotation not available (537 aa)
 
 
  0.969
ilvG
annotation not available (548 aa)
 
 
  0.964
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (469 aa)
 
   
  0.841
Your Current Organism:
Sinorhizobium fredii NGR234
NCBI taxonomy Id: 394
Other names: Ensifer fredii NGR234, Plasmid pNGR234a, Rhizobium sp. (strain NGR234), Rhizobium sp. NGR234, S. fredii NGR234, Sinorhizobium fredii NGR234, Sinorhizobium sp. NGR234
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