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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_3003Glycosidase PH1107-related; Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose; Belongs to the glycosyl hydrolase 130 family. (396 aa)    
Predicted Functional Partners:
Ccel_3002
N-acylglucosamine 2-epimerase; Catalyzes the reversible epimerization of cellobiose to 4-O- beta-D-glucopyranosyl-D-mannose (Glc-Man).
 
   
 0.959
Ccel_3001
PFAM: glycosidase PH1107-related; KEGG: tpt:Tpet_1543 glycosidase, PH1107-related.
 
    
0.797
Ccel_1262
PFAM: protein of unknown function DUF303 acetylesterase putative; glycoside hydrolase family 2 sugar binding; KEGG: csc:Csac_0206 protein of unknown function DUF303, acetylesterase putative; Belongs to the glycosyl hydrolase 2 family.
 
     0.696
Ccel_0992
PFAM: coagulation factor 5/8 type domain protein; glycoside hydrolase family 2 sugar binding; KEGG: bth:BT_4151 beta-glucuronidase; Belongs to the glycosyl hydrolase 2 family.
 
    0.552
Ccel_2999
Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: bcl:ABC0314 transcriptional regulator.
 
     0.552
Ccel_2997
PFAM: extracellular solute-binding protein family 1; KEGG: sco:SCO6231 sugar transport system sugar-binding lipoprotein.
 
     0.546
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: cth:Cthe_0217 glucose-6-phosphate isomerase; Belongs to the GPI family.
      
 0.499
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
      
 0.499
Ccel_3000
Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: cth:Cthe_2505 LacI family transcription regulator.
 
     0.492
man26A
PFAM: glycoside hydrolase family 26; cellulosome protein dockerin type I; KEGG: cth:Cthe_2811 glycoside hydrolase family protein; Belongs to the glycosyl hydrolase 26 family.
 
   
 0.484
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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