STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLCOG0001: Glutamate-1-semialdehyde aminotransferase, Ralstonia solanacearum; KEGG, K01845. (427 aa)    
Predicted Functional Partners:
hemB
Porphobilinogen synthase; COG0113: Delta-aminolevulinic acid dehydratase, Ralstonia solanacearum; KEGG, K01698; Belongs to the ALAD family.
 
 
 0.998
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.997
hemL-2
COG0001: Glutamate-1-semialdehyde aminotransferase, Pseudomonas aeruginosa; KEGG, K01845; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.961
BAG46845.1
COG1020: Non-ribosomal peptide synthetase modules and related proteins, Pseudomonas aeruginosa.
  
 0.943
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.924
dltC
D-alanine-poly(phosphoribitol) ligase; COG1020: Non-ribosomal peptide synthetase modules and related proteins, Pseudomonas aeruginosa; KEGG, K03367.
 
 0.915
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.882
orbJ
COG1020: Non-ribosomal peptide synthetase modules and related proteins, Pseudomonas aeruginosa; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.807
ribE
COG0307: Riboflavin synthase alpha chain, Ralstonia solanacearum; KEGG, K00793.
     
 0.789
BAG42601.1
COG3321: Polyketide synthase modules and related proteins, Sinorhizobium meliloti.
   
 0.776
Your Current Organism:
Burkholderia multivorans
NCBI taxonomy Id: 395019
Other names: B. multivorans ATCC 17616, Burkholderia multivorans ATCC 17616, Burkholderia multivorans str. ATCC 17616, Burkholderia multivorans strain ATCC 17616
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