STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panCPantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (279 aa)    
Predicted Functional Partners:
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
 0.999
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
 
 0.998
baf
Putative transcriptional regulator; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family.
 
 
 0.987
aptA-2
Beta-alanine-pyruvate transaminase; COG0161: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, Pseudomonas aeruginosa; KEGG, K00822; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 
 0.955
apbA-2
2-dehydropantoate 2-reductase; COG1893: Ketopantoate reductase, Ralstonia solanacearum; KEGG, K00077.
    
 0.953
gabT
COG0160: 4-aminobutyrate aminotransferase and related aminotransferases, Ralstonia solanacearum; KEGG, K00823; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.953
cmk
COG0283: Cytidylate kinase, Ralstonia solanacearum; KEGG, K00945.
   
  0.928
dfp
Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
 
 0.927
apbA-4
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.908
aptA
Beta-alanine-pyruvate transaminase; COG0161: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, Ralstonia solanacearum; KEGG, K00822; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 
 0.905
Your Current Organism:
Burkholderia multivorans
NCBI taxonomy Id: 395019
Other names: B. multivorans ATCC 17616, Burkholderia multivorans ATCC 17616, Burkholderia multivorans str. ATCC 17616, Burkholderia multivorans strain ATCC 17616
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