STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioBBiotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (339 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.999
bioF-2
8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
 
 0.972
bioA-3
COG0161: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, Ralstonia solanacearum; KEGG, K00833; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.964
birA
COG0340: Biotin-(acetyl-CoA carboxylase) ligase, Ralstonia solanacearum; KEGG, K01947.
  
 
 0.942
bioF
8-amino-7-oxononanoate synthase; COG0156: 7-keto-8-aminopelargonate synthetase and related enzymes, Sinorhizobium meliloti; KEGG, K00652.
 
 0.826
kbl
Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
 
 
 0.802
thiC
Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
  
 0.773
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
    
 0.693
bioA-4
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; EC 1.2.1.8; KEGG, K00130; frame shift-mutated betaine-aldehyde dehydrogenase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.683
aptA-2
Beta-alanine-pyruvate transaminase; COG0161: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, Pseudomonas aeruginosa; KEGG, K00822; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.672
Your Current Organism:
Burkholderia multivorans
NCBI taxonomy Id: 395019
Other names: B. multivorans ATCC 17616, Burkholderia multivorans ATCC 17616, Burkholderia multivorans str. ATCC 17616, Burkholderia multivorans strain ATCC 17616
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