node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BAG42313.1 | BAG47373.1 | BMULJ_00340 | BMULJ_05543 | Hypothetical chaperone protein; COG0443: Molecular chaperone, Ralstonia solanacearum; KEGG, K04046. | Hypothetical protein. | 0.957 |
BAG42313.1 | clpP | BMULJ_00340 | BMULJ_01896 | Hypothetical chaperone protein; COG0443: Molecular chaperone, Ralstonia solanacearum; KEGG, K04046. | ATP-dependent Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.560 |
BAG42313.1 | clpP-2 | BMULJ_00340 | BMULJ_04636 | Hypothetical chaperone protein; COG0443: Molecular chaperone, Ralstonia solanacearum; KEGG, K04046. | COG0740: Protease subunit of ATP-dependent Clp proteases, Mesorhizobium loti; KEGG, K01358; Belongs to the peptidase S14 family. | 0.560 |
BAG42313.1 | dnaJ | BMULJ_00340 | BMULJ_00606 | Hypothetical chaperone protein; COG0443: Molecular chaperone, Ralstonia solanacearum; KEGG, K04046. | Molecular chaperone; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | 0.981 |
BAG42313.1 | grpE | BMULJ_00340 | BMULJ_00603 | Hypothetical chaperone protein; COG0443: Molecular chaperone, Ralstonia solanacearum; KEGG, K04046. | Molecular chaperone; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...] | 0.986 |
BAG42313.1 | hrcA | BMULJ_00340 | BMULJ_00599 | Hypothetical chaperone protein; COG0443: Molecular chaperone, Ralstonia solanacearum; KEGG, K04046. | Heat-inducible transcriptional repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.811 |
BAG45282.1 | BAG45283.1 | BMULJ_03409 | BMULJ_03410 | COG0443: Molecular chaperone, Vibrio cholerae; Belongs to the heat shock protein 70 family. | COG0443: Molecular chaperone, Vibrio cholerae. | 0.824 |
BAG45282.1 | BAG47373.1 | BMULJ_03409 | BMULJ_05543 | COG0443: Molecular chaperone, Vibrio cholerae; Belongs to the heat shock protein 70 family. | Hypothetical protein. | 0.957 |
BAG45282.1 | clpP | BMULJ_03409 | BMULJ_01896 | COG0443: Molecular chaperone, Vibrio cholerae; Belongs to the heat shock protein 70 family. | ATP-dependent Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.570 |
BAG45282.1 | clpP-2 | BMULJ_03409 | BMULJ_04636 | COG0443: Molecular chaperone, Vibrio cholerae; Belongs to the heat shock protein 70 family. | COG0740: Protease subunit of ATP-dependent Clp proteases, Mesorhizobium loti; KEGG, K01358; Belongs to the peptidase S14 family. | 0.570 |
BAG45282.1 | dnaJ | BMULJ_03409 | BMULJ_00606 | COG0443: Molecular chaperone, Vibrio cholerae; Belongs to the heat shock protein 70 family. | Molecular chaperone; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | 0.980 |
BAG45282.1 | grpE | BMULJ_03409 | BMULJ_00603 | COG0443: Molecular chaperone, Vibrio cholerae; Belongs to the heat shock protein 70 family. | Molecular chaperone; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...] | 0.986 |
BAG45282.1 | hrcA | BMULJ_03409 | BMULJ_00599 | COG0443: Molecular chaperone, Vibrio cholerae; Belongs to the heat shock protein 70 family. | Heat-inducible transcriptional repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.786 |
BAG45283.1 | BAG45282.1 | BMULJ_03410 | BMULJ_03409 | COG0443: Molecular chaperone, Vibrio cholerae. | COG0443: Molecular chaperone, Vibrio cholerae; Belongs to the heat shock protein 70 family. | 0.824 |
BAG45283.1 | BAG47373.1 | BMULJ_03410 | BMULJ_05543 | COG0443: Molecular chaperone, Vibrio cholerae. | Hypothetical protein. | 0.957 |
BAG45283.1 | clpP | BMULJ_03410 | BMULJ_01896 | COG0443: Molecular chaperone, Vibrio cholerae. | ATP-dependent Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.570 |
BAG45283.1 | clpP-2 | BMULJ_03410 | BMULJ_04636 | COG0443: Molecular chaperone, Vibrio cholerae. | COG0740: Protease subunit of ATP-dependent Clp proteases, Mesorhizobium loti; KEGG, K01358; Belongs to the peptidase S14 family. | 0.570 |
BAG45283.1 | dnaJ | BMULJ_03410 | BMULJ_00606 | COG0443: Molecular chaperone, Vibrio cholerae. | Molecular chaperone; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | 0.980 |
BAG45283.1 | grpE | BMULJ_03410 | BMULJ_00603 | COG0443: Molecular chaperone, Vibrio cholerae. | Molecular chaperone; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...] | 0.986 |
BAG45283.1 | hrcA | BMULJ_03410 | BMULJ_00599 | COG0443: Molecular chaperone, Vibrio cholerae. | Heat-inducible transcriptional repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.786 |