node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Lcho_0382 | dcd | Lcho_0382 | Lcho_2740 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.568 |
Lcho_0382 | dut | Lcho_0382 | Lcho_2644 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.778 |
Lcho_0382 | ndk | Lcho_0382 | Lcho_2872 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.940 |
Lcho_0382 | polA | Lcho_0382 | Lcho_1062 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.828 |
Lcho_0382 | pyrG | Lcho_0382 | Lcho_1176 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.453 |
Lcho_0382 | tmk | Lcho_0382 | Lcho_1878 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.958 |
Lcho_0620 | dcd | Lcho_0620 | Lcho_2740 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.550 |
Lcho_0620 | polA | Lcho_0620 | Lcho_1062 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.444 |
Lcho_2739 | dcd | Lcho_2739 | Lcho_2740 | KEGG: mpt:Mpe_A1206 hypothetical protein. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.489 |
Lcho_2741 | dcd | Lcho_2741 | Lcho_2740 | PFAM: protein of unknown function DUF962; KEGG: psb:Psyr_0242 protein of unknown function DUF962. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.541 |
bamE | dcd | Lcho_0475 | Lcho_2740 | SmpA/OmlA domain protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.521 |
dcd | Lcho_0382 | Lcho_2740 | Lcho_0382 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.568 |
dcd | Lcho_0620 | Lcho_2740 | Lcho_0620 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. | 0.550 |
dcd | Lcho_2739 | Lcho_2740 | Lcho_2739 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | KEGG: mpt:Mpe_A1206 hypothetical protein. | 0.489 |
dcd | Lcho_2741 | Lcho_2740 | Lcho_2741 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | PFAM: protein of unknown function DUF962; KEGG: psb:Psyr_0242 protein of unknown function DUF962. | 0.541 |
dcd | bamE | Lcho_2740 | Lcho_0475 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | SmpA/OmlA domain protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.521 |
dcd | dut | Lcho_2740 | Lcho_2644 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.930 |
dcd | ndk | Lcho_2740 | Lcho_2872 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.928 |
dcd | polA | Lcho_2740 | Lcho_1062 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.443 |
dcd | pyrG | Lcho_2740 | Lcho_1176 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.929 |