node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Lcho_2226 | Lcho_2997 | Lcho_2226 | Lcho_2997 | KEGG: mpt:Mpe_A1374 ATP-dependent helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase domain protein; helicase-associated domain protein; protein of unknown function DUF1605; SMART: AAA ATPase; DEAD-like helicases. | PFAM: helicase domain protein; DbpA RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: bxe:Bxe_A4436 ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family. | 0.658 |
Lcho_2226 | rplD | Lcho_2226 | Lcho_3998 | KEGG: mpt:Mpe_A1374 ATP-dependent helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase domain protein; helicase-associated domain protein; protein of unknown function DUF1605; SMART: AAA ATPase; DEAD-like helicases. | Ribosomal protein L4/L1e; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.678 |
Lcho_2226 | rpsD | Lcho_2226 | Lcho_3924 | KEGG: mpt:Mpe_A1374 ATP-dependent helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase domain protein; helicase-associated domain protein; protein of unknown function DUF1605; SMART: AAA ATPase; DEAD-like helicases. | Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.948 |
Lcho_2487 | Lcho_2997 | Lcho_2487 | Lcho_2997 | GTP-binding protein HSR1-related; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | PFAM: helicase domain protein; DbpA RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: bxe:Bxe_A4436 ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family. | 0.748 |
Lcho_2487 | pnp | Lcho_2487 | Lcho_1497 | GTP-binding protein HSR1-related; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.466 |
Lcho_2487 | rplC | Lcho_2487 | Lcho_3999 | GTP-binding protein HSR1-related; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.883 |
Lcho_2487 | rplD | Lcho_2487 | Lcho_3998 | GTP-binding protein HSR1-related; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | Ribosomal protein L4/L1e; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.821 |
Lcho_2487 | rplM | Lcho_2487 | Lcho_3452 | GTP-binding protein HSR1-related; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.863 |
Lcho_2487 | rplX | Lcho_2487 | Lcho_3938 | GTP-binding protein HSR1-related; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.864 |
Lcho_2995 | Lcho_2997 | Lcho_2995 | Lcho_2997 | PFAM: protein of unknown function RIO1; KEGG: mpt:Mpe_A1034 RIO-type serine/threonine protein kinase. | PFAM: helicase domain protein; DbpA RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: bxe:Bxe_A4436 ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family. | 0.669 |
Lcho_2995 | rplD | Lcho_2995 | Lcho_3998 | PFAM: protein of unknown function RIO1; KEGG: mpt:Mpe_A1034 RIO-type serine/threonine protein kinase. | Ribosomal protein L4/L1e; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.521 |
Lcho_2995 | rpsD | Lcho_2995 | Lcho_3924 | PFAM: protein of unknown function RIO1; KEGG: mpt:Mpe_A1034 RIO-type serine/threonine protein kinase. | Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.909 |
Lcho_2997 | Lcho_2226 | Lcho_2997 | Lcho_2226 | PFAM: helicase domain protein; DbpA RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: bxe:Bxe_A4436 ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family. | KEGG: mpt:Mpe_A1374 ATP-dependent helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase domain protein; helicase-associated domain protein; protein of unknown function DUF1605; SMART: AAA ATPase; DEAD-like helicases. | 0.658 |
Lcho_2997 | Lcho_2487 | Lcho_2997 | Lcho_2487 | PFAM: helicase domain protein; DbpA RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: bxe:Bxe_A4436 ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family. | GTP-binding protein HSR1-related; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.748 |
Lcho_2997 | Lcho_2995 | Lcho_2997 | Lcho_2995 | PFAM: helicase domain protein; DbpA RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: bxe:Bxe_A4436 ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family. | PFAM: protein of unknown function RIO1; KEGG: mpt:Mpe_A1034 RIO-type serine/threonine protein kinase. | 0.669 |
Lcho_2997 | nnrE | Lcho_2997 | Lcho_2854 | PFAM: helicase domain protein; DbpA RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: bxe:Bxe_A4436 ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.749 |
Lcho_2997 | pnp | Lcho_2997 | Lcho_1497 | PFAM: helicase domain protein; DbpA RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: bxe:Bxe_A4436 ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.719 |
Lcho_2997 | rplC | Lcho_2997 | Lcho_3999 | PFAM: helicase domain protein; DbpA RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: bxe:Bxe_A4436 ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family. | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.770 |
Lcho_2997 | rplD | Lcho_2997 | Lcho_3998 | PFAM: helicase domain protein; DbpA RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: bxe:Bxe_A4436 ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family. | Ribosomal protein L4/L1e; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.650 |
Lcho_2997 | rplM | Lcho_2997 | Lcho_3452 | PFAM: helicase domain protein; DbpA RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: bxe:Bxe_A4436 ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.708 |