node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Lcho_0227 | bioB | Lcho_0227 | Lcho_3644 | TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin protein ligase domain protein; biotin/lipoate A/B protein ligase; KEGG: mpt:Mpe_A0263 biotin acetyl-CoA-carboxylase synthetase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.944 |
Lcho_0227 | bioD | Lcho_0227 | Lcho_3643 | TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin protein ligase domain protein; biotin/lipoate A/B protein ligase; KEGG: mpt:Mpe_A0263 biotin acetyl-CoA-carboxylase synthetase. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.482 |
Lcho_0227 | bioF | Lcho_0227 | Lcho_3642 | TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin protein ligase domain protein; biotin/lipoate A/B protein ligase; KEGG: mpt:Mpe_A0263 biotin acetyl-CoA-carboxylase synthetase. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.432 |
Lcho_1738 | Lcho_2434 | Lcho_1738 | Lcho_2434 | PFAM: aminotransferase class-III; KEGG: mpt:Mpe_A1902 putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | PFAM: thiamine monophosphate synthase; Phosphomethylpyrimidine kinase type-1; KEGG: mpt:Mpe_A1606 phosphomethylpyrimidine kinase / thiamine-phosphate pyrophosphorylase. | 0.414 |
Lcho_1738 | bioB | Lcho_1738 | Lcho_3644 | PFAM: aminotransferase class-III; KEGG: mpt:Mpe_A1902 putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.704 |
Lcho_1738 | bioD | Lcho_1738 | Lcho_3643 | PFAM: aminotransferase class-III; KEGG: mpt:Mpe_A1902 putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.712 |
Lcho_1738 | bioF | Lcho_1738 | Lcho_3642 | PFAM: aminotransferase class-III; KEGG: mpt:Mpe_A1902 putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.560 |
Lcho_1742 | Lcho_2434 | Lcho_1742 | Lcho_2434 | PFAM: aminotransferase class-III; KEGG: mpt:Mpe_A1898 beta alanine--pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | PFAM: thiamine monophosphate synthase; Phosphomethylpyrimidine kinase type-1; KEGG: mpt:Mpe_A1606 phosphomethylpyrimidine kinase / thiamine-phosphate pyrophosphorylase. | 0.414 |
Lcho_1742 | bioB | Lcho_1742 | Lcho_3644 | PFAM: aminotransferase class-III; KEGG: mpt:Mpe_A1898 beta alanine--pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.723 |
Lcho_1742 | bioD | Lcho_1742 | Lcho_3643 | PFAM: aminotransferase class-III; KEGG: mpt:Mpe_A1898 beta alanine--pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.717 |
Lcho_1742 | bioF | Lcho_1742 | Lcho_3642 | PFAM: aminotransferase class-III; KEGG: mpt:Mpe_A1898 beta alanine--pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.589 |
Lcho_2434 | Lcho_1738 | Lcho_2434 | Lcho_1738 | PFAM: thiamine monophosphate synthase; Phosphomethylpyrimidine kinase type-1; KEGG: mpt:Mpe_A1606 phosphomethylpyrimidine kinase / thiamine-phosphate pyrophosphorylase. | PFAM: aminotransferase class-III; KEGG: mpt:Mpe_A1902 putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.414 |
Lcho_2434 | Lcho_1742 | Lcho_2434 | Lcho_1742 | PFAM: thiamine monophosphate synthase; Phosphomethylpyrimidine kinase type-1; KEGG: mpt:Mpe_A1606 phosphomethylpyrimidine kinase / thiamine-phosphate pyrophosphorylase. | PFAM: aminotransferase class-III; KEGG: mpt:Mpe_A1898 beta alanine--pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.414 |
Lcho_2434 | Lcho_3641 | Lcho_2434 | Lcho_3641 | PFAM: thiamine monophosphate synthase; Phosphomethylpyrimidine kinase type-1; KEGG: mpt:Mpe_A1606 phosphomethylpyrimidine kinase / thiamine-phosphate pyrophosphorylase. | TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: bpt:Bpet0011 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.414 |
Lcho_2434 | bioB | Lcho_2434 | Lcho_3644 | PFAM: thiamine monophosphate synthase; Phosphomethylpyrimidine kinase type-1; KEGG: mpt:Mpe_A1606 phosphomethylpyrimidine kinase / thiamine-phosphate pyrophosphorylase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.593 |
Lcho_2434 | bioD | Lcho_2434 | Lcho_3643 | PFAM: thiamine monophosphate synthase; Phosphomethylpyrimidine kinase type-1; KEGG: mpt:Mpe_A1606 phosphomethylpyrimidine kinase / thiamine-phosphate pyrophosphorylase. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.507 |
Lcho_2434 | bioF | Lcho_2434 | Lcho_3642 | PFAM: thiamine monophosphate synthase; Phosphomethylpyrimidine kinase type-1; KEGG: mpt:Mpe_A1606 phosphomethylpyrimidine kinase / thiamine-phosphate pyrophosphorylase. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.425 |
Lcho_2434 | thiC | Lcho_2434 | Lcho_2430 | PFAM: thiamine monophosphate synthase; Phosphomethylpyrimidine kinase type-1; KEGG: mpt:Mpe_A1606 phosphomethylpyrimidine kinase / thiamine-phosphate pyrophosphorylase. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.999 |
Lcho_3641 | Lcho_2434 | Lcho_3641 | Lcho_2434 | TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: bpt:Bpet0011 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | PFAM: thiamine monophosphate synthase; Phosphomethylpyrimidine kinase type-1; KEGG: mpt:Mpe_A1606 phosphomethylpyrimidine kinase / thiamine-phosphate pyrophosphorylase. | 0.414 |
Lcho_3641 | Lcho_3645 | Lcho_3641 | Lcho_3645 | TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: bpt:Bpet0011 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | PFAM: cytochrome P450; KEGG: pna:Pnap_4029 cytochrome P450. | 0.626 |