node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACL42917.1 | ACL42935.1 | Cyan7425_0526 | Cyan7425_0544 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: amr:AM1_1662 ferredoxin-dependent glutamate synthase. | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: tel:tlr1296 acetolactate synthase large subunit. | 0.564 |
ACL42917.1 | ACL43106.1 | Cyan7425_0526 | Cyan7425_0719 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: amr:AM1_1662 ferredoxin-dependent glutamate synthase. | KEGG: tel:tll0880 acetolactate synthase small subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; acetolactate synthase small subunit. | 0.586 |
ACL42917.1 | ACL43704.1 | Cyan7425_0526 | Cyan7425_1327 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: amr:AM1_1662 ferredoxin-dependent glutamate synthase. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.660 |
ACL42917.1 | ACL44725.1 | Cyan7425_0526 | Cyan7425_2367 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: amr:AM1_1662 ferredoxin-dependent glutamate synthase. | TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: npu:Npun_F0430 homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.458 |
ACL42917.1 | ACL45057.1 | Cyan7425_0526 | Cyan7425_2710 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: amr:AM1_1662 ferredoxin-dependent glutamate synthase. | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: tel:tll1824 acetolactate synthase large subunit; Belongs to the TPP enzyme family. | 0.564 |
ACL42917.1 | ilvC | Cyan7425_0526 | Cyan7425_1343 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: amr:AM1_1662 ferredoxin-dependent glutamate synthase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.758 |
ACL42917.1 | ilvD | Cyan7425_0526 | Cyan7425_0847 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: amr:AM1_1662 ferredoxin-dependent glutamate synthase. | KEGG: tel:tll1057 dihydroxyacid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.889 |
ACL42917.1 | leuA | Cyan7425_0526 | Cyan7425_0344 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: amr:AM1_1662 ferredoxin-dependent glutamate synthase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.458 |
ACL42917.1 | leuB | Cyan7425_0526 | Cyan7425_2577 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: amr:AM1_1662 ferredoxin-dependent glutamate synthase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.653 |
ACL42917.1 | leuC | Cyan7425_0526 | Cyan7425_1136 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: amr:AM1_1662 ferredoxin-dependent glutamate synthase. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.750 |
ACL42935.1 | ACL42917.1 | Cyan7425_0544 | Cyan7425_0526 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: tel:tlr1296 acetolactate synthase large subunit. | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: amr:AM1_1662 ferredoxin-dependent glutamate synthase. | 0.564 |
ACL42935.1 | ACL43106.1 | Cyan7425_0544 | Cyan7425_0719 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: tel:tlr1296 acetolactate synthase large subunit. | KEGG: tel:tll0880 acetolactate synthase small subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; acetolactate synthase small subunit. | 0.999 |
ACL42935.1 | ACL43704.1 | Cyan7425_0544 | Cyan7425_1327 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: tel:tlr1296 acetolactate synthase large subunit. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.733 |
ACL42935.1 | ACL44725.1 | Cyan7425_0544 | Cyan7425_2367 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: tel:tlr1296 acetolactate synthase large subunit. | TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: npu:Npun_F0430 homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.780 |
ACL42935.1 | ACL45057.1 | Cyan7425_0544 | Cyan7425_2710 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: tel:tlr1296 acetolactate synthase large subunit. | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: tel:tll1824 acetolactate synthase large subunit; Belongs to the TPP enzyme family. | 0.919 |
ACL42935.1 | ilvC | Cyan7425_0544 | Cyan7425_1343 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: tel:tlr1296 acetolactate synthase large subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.994 |
ACL42935.1 | ilvD | Cyan7425_0544 | Cyan7425_0847 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: tel:tlr1296 acetolactate synthase large subunit. | KEGG: tel:tll1057 dihydroxyacid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.969 |
ACL42935.1 | leuA | Cyan7425_0544 | Cyan7425_0344 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: tel:tlr1296 acetolactate synthase large subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.953 |
ACL42935.1 | leuB | Cyan7425_0544 | Cyan7425_2577 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: tel:tlr1296 acetolactate synthase large subunit. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.981 |
ACL42935.1 | leuC | Cyan7425_0544 | Cyan7425_1136 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: tel:tlr1296 acetolactate synthase large subunit. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.702 |