STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uvrBExcinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (665 aa)    
Predicted Functional Partners:
uvrA
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
 
 0.999
uvrC
Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
 0.998
ACL44447.1
KEGG: tel:tlr0066 hypothetical protein.
  
 
 0.976
ACL44661.1
PFAM: UvrD/REP helicase; Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: nth:Nther_2137 DNA polymerase III, epsilon subunit.
 
 
 0.827
ACL43883.1
TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; KEGG: amr:AM1_1428 ATP-dependent DNA helicase PcrA.
 
 
 0.816
ACL46425.1
PFAM: UvrD/REP helicase; KEGG: sru:SRU_0718 ATP-dependent DNA helicase.
 
 
 0.803
ACL47420.1
Superfamily I DNA and RNA helicase-like protein; KEGG: ter:Tery_2383 TPR repeat-containing protein.
  
 
 0.679
ACL43397.1
KEGG: amr:AM1_4478 hypothetical protein.
  
 
 0.651
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.579
pheT
phenylalanyl-tRNA synthetase, beta subunit; KEGG: ana:alr4958 phenylalanyl-tRNA synthetase; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
   
 0.566
Your Current Organism:
Cyanothece sp. PCC7425
NCBI taxonomy Id: 395961
Other names: C. sp. PCC 7425, Cyanothece sp. ATCC 29141, Cyanothece sp. PCC 7425, Synechococcus sp. PCC 7425
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.