node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bind_0691 | ddl | Bind_0691 | Bind_0695 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | D-alanine--D-alanine ligase; Cell wall formation. | 0.972 |
Bind_0691 | ftsA | Bind_0691 | Bind_0697 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.951 |
Bind_0691 | ftsQ | Bind_0691 | Bind_0696 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | 0.990 |
Bind_0691 | ftsZ | Bind_0691 | Bind_0698 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.813 |
Bind_0691 | minC | Bind_0691 | Bind_1704 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.446 |
Bind_0691 | murC | Bind_0691 | Bind_0693 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.990 |
Bind_0691 | murE | Bind_0691 | Bind_0687 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.885 |
Bind_0691 | murF | Bind_0691 | Bind_0688 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.920 |
Bind_0691 | murG | Bind_0691 | Bind_0692 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.987 |
ddl | Bind_0691 | Bind_0695 | Bind_0691 | D-alanine--D-alanine ligase; Cell wall formation. | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | 0.972 |
ddl | ftsA | Bind_0695 | Bind_0697 | D-alanine--D-alanine ligase; Cell wall formation. | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.975 |
ddl | ftsQ | Bind_0695 | Bind_0696 | D-alanine--D-alanine ligase; Cell wall formation. | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | 0.976 |
ddl | ftsZ | Bind_0695 | Bind_0698 | D-alanine--D-alanine ligase; Cell wall formation. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.747 |
ddl | murC | Bind_0695 | Bind_0693 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.995 |
ddl | murE | Bind_0695 | Bind_0687 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.897 |
ddl | murF | Bind_0695 | Bind_0688 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.996 |
ddl | murG | Bind_0695 | Bind_0692 | D-alanine--D-alanine ligase; Cell wall formation. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.981 |
ftsA | Bind_0691 | Bind_0697 | Bind_0691 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | 0.951 |
ftsA | ddl | Bind_0697 | Bind_0695 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | D-alanine--D-alanine ligase; Cell wall formation. | 0.975 |
ftsA | ftsQ | Bind_0697 | Bind_0696 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | 0.990 |