STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (319 aa)    
Predicted Functional Partners:
KRN58848.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.984
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.956
KRN58771.1
Pyruvate dehydrogenase E1 component beta subunit.
   
 0.952
KRN58184.1
Acetolactate synthase, catabolic; Belongs to the TPP enzyme family.
  
 0.945
pdhA
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 
 0.944
KRN58451.1
Xylulose-5-phosphate phosphoketolase.
     
 0.943
zwf
Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
   
 
 0.932
KRN58957.1
Malate dehydrogenase.
  
 0.931
KRN58442.1
Transketolase; Belongs to the transketolase family.
  
 
 0.922
KRN59175.1
Transaldolase.
   
 0.920
Your Current Organism:
Lactobacillus secaliphilus
NCBI taxonomy Id: 396268
Other names: CCUG 53218, DSM 17896, JCM 15613, L. secaliphilus, Lactobacillus secaliphilus Ehrmann et al. 2007
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.