node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tgr7_0125 | Tgr7_0506 | Tgr7_0125 | Tgr7_0506 | Histidine kinase; KEGG: hch:HCH_06299 signal transduction histidine kinase. | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; KEGG: ter:Tery_3412 adenylate/guanylate cyclase. | 0.999 |
Tgr7_0125 | bioF | Tgr7_0125 | Tgr7_0133 | Histidine kinase; KEGG: hch:HCH_06299 signal transduction histidine kinase. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.539 |
Tgr7_0125 | purL | Tgr7_0125 | Tgr7_1501 | Histidine kinase; KEGG: hch:HCH_06299 signal transduction histidine kinase. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.562 |
Tgr7_0132 | bioF | Tgr7_0132 | Tgr7_0133 | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: glo:Glov_0563 methyltransferase type 11. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.824 |
Tgr7_0506 | Tgr7_0125 | Tgr7_0506 | Tgr7_0125 | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; KEGG: ter:Tery_3412 adenylate/guanylate cyclase. | Histidine kinase; KEGG: hch:HCH_06299 signal transduction histidine kinase. | 0.999 |
Tgr7_0506 | Tgr7_1696 | Tgr7_0506 | Tgr7_1696 | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; KEGG: ter:Tery_3412 adenylate/guanylate cyclase. | PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: bph:Bphy_5916 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. | 0.404 |
Tgr7_0506 | bioF | Tgr7_0506 | Tgr7_0133 | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; KEGG: ter:Tery_3412 adenylate/guanylate cyclase. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.520 |
Tgr7_0506 | purL | Tgr7_0506 | Tgr7_1501 | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; KEGG: ter:Tery_3412 adenylate/guanylate cyclase. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.567 |
Tgr7_1696 | Tgr7_0506 | Tgr7_1696 | Tgr7_0506 | PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: bph:Bphy_5916 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; KEGG: ter:Tery_3412 adenylate/guanylate cyclase. | 0.404 |
Tgr7_1696 | bioF | Tgr7_1696 | Tgr7_0133 | PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: bph:Bphy_5916 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.530 |
Tgr7_1696 | purL | Tgr7_1696 | Tgr7_1501 | PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: bph:Bphy_5916 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.495 |
Tgr7_3014 | bioB | Tgr7_3014 | Tgr7_0131 | KEGG: aha:AHA_0299 putative pimeloyl-BioC--CoA transferase BioH. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.445 |
Tgr7_3014 | bioC | Tgr7_3014 | Tgr7_3013 | KEGG: aha:AHA_0299 putative pimeloyl-BioC--CoA transferase BioH. | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.995 |
Tgr7_3014 | bioD | Tgr7_3014 | Tgr7_2887 | KEGG: aha:AHA_0299 putative pimeloyl-BioC--CoA transferase BioH. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.600 |
Tgr7_3014 | bioF | Tgr7_3014 | Tgr7_0133 | KEGG: aha:AHA_0299 putative pimeloyl-BioC--CoA transferase BioH. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.974 |
bioA | bioB | Tgr7_1722 | Tgr7_0131 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.986 |
bioA | bioC | Tgr7_1722 | Tgr7_3013 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.575 |
bioA | bioD | Tgr7_1722 | Tgr7_2887 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.998 |
bioA | bioF | Tgr7_1722 | Tgr7_0133 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.986 |
bioB | Tgr7_3014 | Tgr7_0131 | Tgr7_3014 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | KEGG: aha:AHA_0299 putative pimeloyl-BioC--CoA transferase BioH. | 0.445 |