node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tgr7_1828 | dut | Tgr7_1828 | Tgr7_0103 | KEGG: mca:MCA1995 DNA polymerase III, delta prime subunit. | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.422 |
Tgr7_1828 | tmk | Tgr7_1828 | Tgr7_1829 | KEGG: mca:MCA1995 DNA polymerase III, delta prime subunit. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.960 |
Tgr7_2431 | Tgr7_2930 | Tgr7_2431 | Tgr7_2930 | KEGG: ttj:TTHA1328 5'-nucleotidase precursor; Belongs to the 5'-nucleotidase family. | KEGG: pau:PA14_68390 putative hydrolase. | 0.902 |
Tgr7_2431 | dut | Tgr7_2431 | Tgr7_0103 | KEGG: ttj:TTHA1328 5'-nucleotidase precursor; Belongs to the 5'-nucleotidase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.900 |
Tgr7_2431 | surE | Tgr7_2431 | Tgr7_1432 | KEGG: ttj:TTHA1328 5'-nucleotidase precursor; Belongs to the 5'-nucleotidase family. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.910 |
Tgr7_2431 | thyA | Tgr7_2431 | Tgr7_2747 | KEGG: ttj:TTHA1328 5'-nucleotidase precursor; Belongs to the 5'-nucleotidase family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.902 |
Tgr7_2431 | tmk | Tgr7_2431 | Tgr7_1829 | KEGG: ttj:TTHA1328 5'-nucleotidase precursor; Belongs to the 5'-nucleotidase family. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.911 |
Tgr7_2614 | Tgr7_2615 | Tgr7_2614 | Tgr7_2615 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.999 |
Tgr7_2614 | Tgr7_2673 | Tgr7_2614 | Tgr7_2673 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | KEGG: aeh:Mlg_1471 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent. | 0.999 |
Tgr7_2614 | ndk | Tgr7_2614 | Tgr7_2052 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.916 |
Tgr7_2614 | tmk | Tgr7_2614 | Tgr7_1829 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.927 |
Tgr7_2615 | Tgr7_2614 | Tgr7_2615 | Tgr7_2614 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.999 |
Tgr7_2615 | Tgr7_2673 | Tgr7_2615 | Tgr7_2673 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | KEGG: aeh:Mlg_1471 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent. | 0.957 |
Tgr7_2615 | dut | Tgr7_2615 | Tgr7_0103 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.815 |
Tgr7_2615 | ndk | Tgr7_2615 | Tgr7_2052 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.935 |
Tgr7_2615 | thyA | Tgr7_2615 | Tgr7_2747 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.824 |
Tgr7_2615 | tmk | Tgr7_2615 | Tgr7_1829 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.953 |
Tgr7_2673 | Tgr7_2614 | Tgr7_2673 | Tgr7_2614 | KEGG: aeh:Mlg_1471 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.999 |
Tgr7_2673 | Tgr7_2615 | Tgr7_2673 | Tgr7_2615 | KEGG: aeh:Mlg_1471 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.957 |
Tgr7_2673 | dut | Tgr7_2673 | Tgr7_0103 | KEGG: aeh:Mlg_1471 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent. | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.899 |