node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aave_0002 | Aave_0375 | Aave_0002 | Aave_0375 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: reu:Reut_B3895 DNA ligase (ATP). | 0.966 |
Aave_0002 | Aave_3411 | Aave_0002 | Aave_3411 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: rfr:Rfer_2256 DNA-directed DNA polymerase. | 0.999 |
Aave_0002 | ligA | Aave_0002 | Aave_2841 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.439 |
Aave_0002 | polA | Aave_0002 | Aave_1930 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.997 |
Aave_0374 | Aave_0375 | Aave_0374 | Aave_0375 | KEGG: ppu:PP_1106 putative mRNA 3-end processing factor. | PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: reu:Reut_B3895 DNA ligase (ATP). | 0.995 |
Aave_0374 | Aave_0376 | Aave_0374 | Aave_0376 | KEGG: ppu:PP_1106 putative mRNA 3-end processing factor. | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases-like; KEGG: reu:Reut_A1853 helicase, C-terminal:DEAD/DEAH box helicase, N-terminal. | 0.928 |
Aave_0374 | Aave_0377 | Aave_0374 | Aave_0377 | KEGG: ppu:PP_1106 putative mRNA 3-end processing factor. | PFAM: metallophosphoesterase; KEGG: ppu:PP_1102 hypothetical protein. | 0.907 |
Aave_0374 | Aave_1492 | Aave_0374 | Aave_1492 | KEGG: ppu:PP_1106 putative mRNA 3-end processing factor. | KEGG: bxe:Bxe_B1162 putative DNA topoisomerase, type I. | 0.552 |
Aave_0374 | polA | Aave_0374 | Aave_1930 | KEGG: ppu:PP_1106 putative mRNA 3-end processing factor. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.750 |
Aave_0375 | Aave_0002 | Aave_0375 | Aave_0002 | PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: reu:Reut_B3895 DNA ligase (ATP). | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.966 |
Aave_0375 | Aave_0374 | Aave_0375 | Aave_0374 | PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: reu:Reut_B3895 DNA ligase (ATP). | KEGG: ppu:PP_1106 putative mRNA 3-end processing factor. | 0.995 |
Aave_0375 | Aave_0376 | Aave_0375 | Aave_0376 | PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: reu:Reut_B3895 DNA ligase (ATP). | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases-like; KEGG: reu:Reut_A1853 helicase, C-terminal:DEAD/DEAH box helicase, N-terminal. | 0.917 |
Aave_0375 | Aave_0377 | Aave_0375 | Aave_0377 | PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: reu:Reut_B3895 DNA ligase (ATP). | PFAM: metallophosphoesterase; KEGG: ppu:PP_1102 hypothetical protein. | 0.920 |
Aave_0375 | Aave_1492 | Aave_0375 | Aave_1492 | PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: reu:Reut_B3895 DNA ligase (ATP). | KEGG: bxe:Bxe_B1162 putative DNA topoisomerase, type I. | 0.648 |
Aave_0375 | Aave_3411 | Aave_0375 | Aave_3411 | PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: reu:Reut_B3895 DNA ligase (ATP). | KEGG: rfr:Rfer_2256 DNA-directed DNA polymerase. | 0.714 |
Aave_0375 | Aave_4175 | Aave_0375 | Aave_4175 | PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: reu:Reut_B3895 DNA ligase (ATP). | D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase; TIGRFAM: histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: pol:Bpro_4201 histidinol-phosphate phosphatase. | 0.632 |
Aave_0375 | ku | Aave_0375 | Aave_2520 | PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: reu:Reut_B3895 DNA ligase (ATP). | Ku domain protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.631 |
Aave_0375 | ligA | Aave_0375 | Aave_2841 | PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: reu:Reut_B3895 DNA ligase (ATP). | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.916 |
Aave_0375 | polA | Aave_0375 | Aave_1930 | PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: reu:Reut_B3895 DNA ligase (ATP). | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.898 |
Aave_0376 | Aave_0374 | Aave_0376 | Aave_0374 | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases-like; KEGG: reu:Reut_A1853 helicase, C-terminal:DEAD/DEAH box helicase, N-terminal. | KEGG: ppu:PP_1106 putative mRNA 3-end processing factor. | 0.928 |