node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
argS | guaA | Aave_0414 | Aave_3367 | KEGG: rfr:Rfer_0773 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.966 |
argS | pnp | Aave_0414 | Aave_1259 | KEGG: rfr:Rfer_0773 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. | 3' exoribonuclease; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.593 |
argS | pyrG | Aave_0414 | Aave_1327 | KEGG: rfr:Rfer_0773 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.843 |
argS | rplE | Aave_0414 | Aave_0613 | KEGG: rfr:Rfer_0773 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. | LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.602 |
argS | rplF | Aave_0414 | Aave_0616 | KEGG: rfr:Rfer_0773 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. | LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.578 |
argS | rplM | Aave_0414 | Aave_4053 | KEGG: rfr:Rfer_0773 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.792 |
argS | rplN | Aave_0414 | Aave_0611 | KEGG: rfr:Rfer_0773 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. | LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.441 |
argS | rpsB | Aave_0414 | Aave_1823 | KEGG: rfr:Rfer_0773 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. | PFAM: ribosomal protein S2; KEGG: pol:Bpro_2695 ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.425 |
dcd | ndk | Aave_1144 | Aave_1420 | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.927 |
dcd | pyrG | Aave_1144 | Aave_1327 | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.925 |
guaA | argS | Aave_3367 | Aave_0414 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | KEGG: rfr:Rfer_0773 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. | 0.966 |
guaA | ndk | Aave_3367 | Aave_1420 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.559 |
guaA | pnp | Aave_3367 | Aave_1259 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 3' exoribonuclease; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.739 |
guaA | pyrG | Aave_3367 | Aave_1327 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.981 |
guaA | rplE | Aave_3367 | Aave_0613 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.487 |
guaA | rplM | Aave_3367 | Aave_4053 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.822 |
guaA | rplN | Aave_3367 | Aave_0611 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.584 |
guaA | rpsB | Aave_3367 | Aave_1823 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | PFAM: ribosomal protein S2; KEGG: pol:Bpro_2695 ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.653 |
ndk | dcd | Aave_1420 | Aave_1144 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.927 |
ndk | guaA | Aave_1420 | Aave_3367 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.559 |