STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (475 aa)    
Predicted Functional Partners:
Aave_1357
Adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: fra:Francci3_4092 S-adenosyl-L-homocysteine hydrolase.
  
  
  0.972
Aave_2779
PFAM: Methionine synthase, vitamin-B12 independent; Cobalamin-independent synthase MetE, N-terminal domain protein; KEGG: pol:Bpro_3466 methionine synthase, vitamin-B12 independent.
  
 
 0.963
Aave_0174
Methionine synthase (B12-dependent); PFAM: homocysteine S-methyltransferase; KEGG: pol:Bpro_0172 5-methyltetrahydrofolate--homocysteine S-methyltransferase.
  
 
 0.922
Aave_0214
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.921
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 0.914
Aave_3021
PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzyme; KEGG: rfr:Rfer_2294 Cys/Met metabolism pyridoxal-phosphate-dependent enzyme.
  
 0.914
Aave_2997
KEGG: pol:Bpro_1836 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzyme; aromatic amino acid beta-eliminating lyase/threonine aldolase.
     
 0.908
Aave_3089
KEGG: reu:Reut_B4968 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzyme; DegT/DnrJ/EryC1/StrS aminotransferase.
     
 0.908
Aave_4573
Methylthioadenosine nucleosidase; PFAM: purine and other phosphorylases, family 1; KEGG: net:Neut_1886 methylthioadenosine nucleosidase.
    
 0.906
Aave_0557
TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: xac:XAC2213 cytosine-specific DNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
     
 0.902
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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