STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
top6ADNA topoisomerase (ATP-hydrolyzing); Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (369 aa)    
Predicted Functional Partners:
top6B
DNA topoisomerase VI, B subunit; Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
 
 
 0.982
radA
DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
 
 
 0.799
Cmaq_0976
PFAM: deoxyhypusine synthase; KEGG: pai:PAE3487 deoxyhypusine synthase.
 
   
 0.647
Cmaq_1706
PFAM: ERCC4 domain protein; KEGG: pis:Pisl_1707 ERCC4 domain protein.
    
 
 0.607
dnaG
TOPRIM domain protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
   
 0.568
Cmaq_1553
PFAM: histidine triad (HIT) protein; KEGG: hbu:Hbut_0970 universally conserved protein.
       0.557
Cmaq_1554
Hypothetical protein.
       0.551
Cmaq_1080
PFAM: metallophosphoesterase; KEGG: pai:PAE2904 exonuclease SbcD, conjectural.
   
 0.549
Cmaq_1081
PFAM: SMC domain protein; KEGG: pis:Pisl_0302 SMC domain protein.
    
 0.535
Cmaq_1882
PFAM: SMC domain protein; KEGG: pai:PAE2280 hypothetical protein.
    
 0.535
Your Current Organism:
Caldivirga maquilingensis
NCBI taxonomy Id: 397948
Other names: C. maquilingensis IC-167, Caldivirga maquilingensis DSM 13496, Caldivirga maquilingensis IC-167, Caldivirga maquilingensis JCM 10307, Caldivirga maquilingensis str. IC-167, Caldivirga maquilingensis strain IC-167
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