STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phrBDeoxyribodipyrimidine photolyase, FAD-binding PhrB; Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation. (479 aa)    
Predicted Functional Partners:
ADC51232.1
Hypothetical protein.
  
  
 0.915
crtM
Triterpenoid carotenoid synthesis, phytoene/squalene synthase; COG1562 Phytoene/squalene synthetase.
 
   
 0.619
clpE
AAA-2 domain ATPase modulates CtsR MecA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.
   
  
 0.610
crtN1
Triterpenoid carotenoid synthesis, Phytoene dehydrogenase (Phytoene desaturase); COG1233 Phytoene dehydrogenase and related proteins.
 
  
 0.598
crtP
Triterpenoid carotenoid synthesis, Phytoene dehydrogenase (Phytoene desaturase); COG1233 Phytoene dehydrogenase and related proteins.
 
  
 0.596
clpP
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
     
 0.581
crtN2
Triterpenoid carotenoid synthesis, phytoene desaturase; COG1233 Phytoene dehydrogenase and related proteins.
 
  
 0.576
ktrD
K+-transporter KtrD; COG0168 Trk-type K+ transport systems, membrane components.
     
 0.562
ADC51389.1
COG2335 Secreted and surface protein containing fasciclin-like repeats.
 
  
 0.557
spo0A
Two-component response regulator central for the initiation of sporulation; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
     
 0.553
Your Current Organism:
Bacillus pseudofirmus
NCBI taxonomy Id: 398511
Other names: B. pseudofirmus OF4, Bacillus pseudofirmus OF4, Bacillus pseudofirmus str. OF4, Bacillus pseudofirmus strain OF4
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