STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)    
Predicted Functional Partners:
pykA
COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.995
pgi
COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.980
fbaA
COG0191 Fructose/tagatose bisphosphate aldolase.
 
 
 0.965
fruK
COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.
  
  
 0.952
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
  
 0.941
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.938
ywjH
Putative translaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.935
mtlD
COG0246 Mannitol-1-phosphate/altronate dehydrogenases.
 
  
 0.932
glpX
COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins.
   
 
 0.919
glpX-2
COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins.
   
 
 0.919
Your Current Organism:
Bacillus pseudofirmus
NCBI taxonomy Id: 398511
Other names: B. pseudofirmus OF4, Bacillus pseudofirmus OF4, Bacillus pseudofirmus str. OF4, Bacillus pseudofirmus strain OF4
Server load: medium (76%) [HD]