STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACD15882.1Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (314 aa)    
Predicted Functional Partners:
ACD15883.1
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 0.998
ACD15881.1
PFAM: Hydratase/decarboxylase; KEGG: bur:Bcep18194_C7646 4-oxalocrotonate decarboxylase.
 
  
 0.978
ACD14998.1
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate).
  
 0.977
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 0.977
ACD15884.1
PFAM: Hydratase/decarboxylase; KEGG: bur:Bcep18194_C7643 4-oxalocrotonate decarboxylase.
 
  
 0.977
leuA-2
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 0.977
ACD19464.1
PFAM: Thiolase; KEGG: bpt:Bpet1121 putative thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 0.932
ACD19929.1
PFAM: phosphate acetyl/butaryl transferase; MaoC domain protein dehydratase; KEGG: bxe:Bxe_B0357 bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
    
 0.909
ACD20165.1
2-oxo-hepta-3-ene-1,7-dioic acid hydratase; KEGG: bxe:Bxe_B2033 putative 2-oxo-hept-3-ene-1,7-dioate hydratase(HpaH); TIGRFAM: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; PFAM: Hydratase/decarboxylase.
 
  
 0.909
ACD17816.1
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
     
 0.908
Your Current Organism:
Paraburkholderia phytofirmans
NCBI taxonomy Id: 398527
Other names: Burkholderia phytofirmans PsJN, Burkholderia sp. PsJN, P. phytofirmans PsJN, Paraburkholderia phytofirmans PsJN
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.