node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACD14698.1 | ACD16207.1 | Bphyt_0271 | Bphyt_1799 | Glycine hydroxymethyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; glycine hydroxymethyltransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mka:MK0122 glycine hydroxymethyltransferase. | PFAM: formyl transferase domain protein; KEGG: bxe:Bxe_A2388 hypothetical protein. | 0.912 |
ACD14698.1 | fmt | Bphyt_0271 | Bphyt_0310 | Glycine hydroxymethyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; glycine hydroxymethyltransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mka:MK0122 glycine hydroxymethyltransferase. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.912 |
ACD14698.1 | folD | Bphyt_0271 | Bphyt_2595 | Glycine hydroxymethyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; glycine hydroxymethyltransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mka:MK0122 glycine hydroxymethyltransferase. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.972 |
ACD14698.1 | gcvT | Bphyt_0271 | Bphyt_3880 | Glycine hydroxymethyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; glycine hydroxymethyltransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mka:MK0122 glycine hydroxymethyltransferase. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.993 |
ACD14698.1 | glyA | Bphyt_0271 | Bphyt_0765 | Glycine hydroxymethyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; glycine hydroxymethyltransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mka:MK0122 glycine hydroxymethyltransferase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.925 |
ACD14698.1 | glyA-2 | Bphyt_0271 | Bphyt_5063 | Glycine hydroxymethyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; glycine hydroxymethyltransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mka:MK0122 glycine hydroxymethyltransferase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.922 |
ACD14698.1 | purH | Bphyt_0271 | Bphyt_3341 | Glycine hydroxymethyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; glycine hydroxymethyltransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mka:MK0122 glycine hydroxymethyltransferase. | KEGG: bxe:Bxe_A0619 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.979 |
ACD14698.1 | purN | Bphyt_0271 | Bphyt_3157 | Glycine hydroxymethyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; glycine hydroxymethyltransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mka:MK0122 glycine hydroxymethyltransferase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.949 |
ACD14698.1 | purU | Bphyt_0271 | Bphyt_0606 | Glycine hydroxymethyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; glycine hydroxymethyltransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mka:MK0122 glycine hydroxymethyltransferase. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.920 |
ACD16207.1 | ACD14698.1 | Bphyt_1799 | Bphyt_0271 | PFAM: formyl transferase domain protein; KEGG: bxe:Bxe_A2388 hypothetical protein. | Glycine hydroxymethyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; glycine hydroxymethyltransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mka:MK0122 glycine hydroxymethyltransferase. | 0.912 |
ACD16207.1 | fmt | Bphyt_1799 | Bphyt_0310 | PFAM: formyl transferase domain protein; KEGG: bxe:Bxe_A2388 hypothetical protein. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.913 |
ACD16207.1 | folD | Bphyt_1799 | Bphyt_2595 | PFAM: formyl transferase domain protein; KEGG: bxe:Bxe_A2388 hypothetical protein. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.961 |
ACD16207.1 | gcvT | Bphyt_1799 | Bphyt_3880 | PFAM: formyl transferase domain protein; KEGG: bxe:Bxe_A2388 hypothetical protein. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.922 |
ACD16207.1 | glyA | Bphyt_1799 | Bphyt_0765 | PFAM: formyl transferase domain protein; KEGG: bxe:Bxe_A2388 hypothetical protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.912 |
ACD16207.1 | glyA-2 | Bphyt_1799 | Bphyt_5063 | PFAM: formyl transferase domain protein; KEGG: bxe:Bxe_A2388 hypothetical protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.912 |
ACD16207.1 | purN | Bphyt_1799 | Bphyt_3157 | PFAM: formyl transferase domain protein; KEGG: bxe:Bxe_A2388 hypothetical protein. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.922 |
ACD18127.1 | folD | Bphyt_3739 | Bphyt_2595 | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: bxe:Bxe_A0197 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.949 |
ACD18127.1 | purN | Bphyt_3739 | Bphyt_3157 | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: bxe:Bxe_A0197 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.917 |
fmt | ACD14698.1 | Bphyt_0310 | Bphyt_0271 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Glycine hydroxymethyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; glycine hydroxymethyltransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mka:MK0122 glycine hydroxymethyltransferase. | 0.912 |
fmt | ACD16207.1 | Bphyt_0310 | Bphyt_1799 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | PFAM: formyl transferase domain protein; KEGG: bxe:Bxe_A2388 hypothetical protein. | 0.913 |