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alaS protein (Burkholderia phytofirmans) - STRING interaction network
"alaS" - Alanine--tRNA ligase in Burkholderia phytofirmans
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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alaSAlanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (874 aa)    
Predicted Functional Partners:
leuS
Leucine--tRNA ligase; TIGRFAM- leucyl-tRNA synthetase; KEGG- bxe-Bxe_A0576 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family (944 aa)
 
 
  0.953
pheT
KEGG- bxe-Bxe_A1376 phenylalanyl-tRNA synthetase subunit beta; TIGRFAM- phenylalanyl-tRNA synthetase, beta subunit (811 aa)
 
 
  0.952
ileS
Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as ’pretransfer’ editing and involves the hydrolysis of activated Val-AMP. The other activity is designated ’posttransfer’ editing and involves deacylation of mischarged Val-tRNA(Ile); Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily (945 aa)
 
 
  0.936
Bphyt_7134
Threonine--tRNA ligase; KEGG- bur-Bcep18194_C7257 threonyl-tRNA synthetase, class IIa; TIGRFAM- threonyl-tRNA synthetase; PFAM- tRNA synthetase class II (G H P and S); Anticodon-binding domain protein (404 aa)
   
 
  0.906
lepA
Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (597 aa)
 
   
  0.902
ftsH
ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family (629 aa)
 
   
  0.880
valS
Valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a "posttransfer" editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily (959 aa)
 
   
  0.865
metG
Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily (711 aa)
   
 
  0.865
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (360 aa)
 
   
  0.841
obg
GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family (373 aa)
 
   
  0.828
Your Current Organism:
Burkholderia phytofirmans
NCBI taxonomy Id: 398527
Other names: B. phytofirmans PsJN, Burkholderia phytofirmans, Burkholderia phytofirmans PsJN, Burkholderia phytofirmans str. PsJN, Burkholderia phytofirmans strain PsJN, Burkholderia sp. PsJN
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