STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Daci_15462-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (312 aa)    
Predicted Functional Partners:
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
   
 0.944
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
 0.914
Daci_1545
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: pna:Pnap_1023 thiamine pyrophosphate enzyme TPP binding domain protein; Belongs to the TPP enzyme family.
     
 0.687
Daci_1547
PFAM: conserved hypothetical protein; KEGG: pol:Bpro_4537 uncharacterized protein UPF0065.
       0.634
Daci_1544
Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pna:Pnap_1024 transcriptional regulator, LysR family.
 
     0.557
Daci_3795
PFAM: 2OG-Fe(II) oxygenase; KEGG: rso:RSc2568 probable alkylated DNA repair protein.
   
    0.497
Daci_1548
PFAM: conserved hypothetical protein; KEGG: pna:Pnap_1019 uncharacterized protein UPF0065.
       0.475
Daci_3339
PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: aav:Aave_1397 mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein.
  
    0.402
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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