node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Spea_1013 | Spea_2863 | Spea_1013 | Spea_2863 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: slo:Shew_1032 glutamate synthase (ferredoxin). | PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: pol:Bpro_3376 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase. | 0.837 |
Spea_1013 | glsA | Spea_1013 | Spea_1111 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: slo:Shew_1032 glutamate synthase (ferredoxin). | PFAM: Glutaminase, core; KEGG: sbm:Shew185_3050 glutaminase; Belongs to the glutaminase family. | 0.959 |
Spea_1013 | murD | Spea_1013 | Spea_3813 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: slo:Shew_1032 glutamate synthase (ferredoxin). | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.452 |
Spea_1013 | murI | Spea_1013 | Spea_0165 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: slo:Shew_1032 glutamate synthase (ferredoxin). | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.607 |
Spea_1122 | alr | Spea_1122 | Spea_3580 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.447 |
Spea_1122 | murI | Spea_1122 | Spea_0165 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.911 |
Spea_1353 | murI | Spea_1353 | Spea_0165 | PFAM: flagellar protein FlaG protein; KEGG: shn:Shewana3_1334 flagellar protein FlaG protein. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.646 |
Spea_2863 | Spea_1013 | Spea_2863 | Spea_1013 | PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: pol:Bpro_3376 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase. | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: slo:Shew_1032 glutamate synthase (ferredoxin). | 0.837 |
Spea_2863 | alr | Spea_2863 | Spea_3580 | PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: pol:Bpro_3376 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.807 |
Spea_2863 | glsA | Spea_2863 | Spea_1111 | PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: pol:Bpro_3376 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase. | PFAM: Glutaminase, core; KEGG: sbm:Shew185_3050 glutaminase; Belongs to the glutaminase family. | 0.830 |
Spea_2863 | murI | Spea_2863 | Spea_0165 | PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: pol:Bpro_3376 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.819 |
alr | Spea_1122 | Spea_3580 | Spea_1122 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.447 |
alr | Spea_2863 | Spea_3580 | Spea_2863 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: pol:Bpro_3376 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase. | 0.807 |
alr | ddl | Spea_3580 | Spea_2422 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-alanine--D-alanine ligase; Cell wall formation. | 0.955 |
alr | mraY | Spea_3580 | Spea_3814 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.483 |
alr | murD | Spea_3580 | Spea_3813 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.668 |
alr | murG | Spea_3580 | Spea_3811 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.513 |
alr | murI | Spea_3580 | Spea_0165 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.715 |
ddl | alr | Spea_2422 | Spea_3580 | D-alanine--D-alanine ligase; Cell wall formation. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.955 |
ddl | mraY | Spea_2422 | Spea_3814 | D-alanine--D-alanine ligase; Cell wall formation. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.925 |