node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Spea_0965 | Spea_0966 | Spea_0965 | Spea_0966 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: she:Shewmr4_2901 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | 0.997 |
Spea_0965 | Spea_0968 | Spea_0965 | Spea_0968 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | KEGG: slo:Shew_1005 rRNA (guanine-N(1)-)-methyltransferase. | 0.546 |
Spea_0965 | Spea_0969 | Spea_0965 | Spea_0969 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; KEGG: slo:Shew_1006 ErfK/YbiS/YcfS/YnhG family protein. | 0.440 |
Spea_0965 | uppP | Spea_0965 | Spea_0967 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Putative undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.728 |
Spea_0966 | Spea_0965 | Spea_0966 | Spea_0965 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: she:Shewmr4_2901 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.997 |
Spea_0966 | Spea_0968 | Spea_0966 | Spea_0968 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: she:Shewmr4_2901 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | KEGG: slo:Shew_1005 rRNA (guanine-N(1)-)-methyltransferase. | 0.547 |
Spea_0966 | Spea_0969 | Spea_0966 | Spea_0969 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: she:Shewmr4_2901 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; KEGG: slo:Shew_1006 ErfK/YbiS/YcfS/YnhG family protein. | 0.443 |
Spea_0966 | uppP | Spea_0966 | Spea_0967 | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: she:Shewmr4_2901 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | Putative undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.728 |
Spea_0968 | Spea_0965 | Spea_0968 | Spea_0965 | KEGG: slo:Shew_1005 rRNA (guanine-N(1)-)-methyltransferase. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.546 |
Spea_0968 | Spea_0966 | Spea_0968 | Spea_0966 | KEGG: slo:Shew_1005 rRNA (guanine-N(1)-)-methyltransferase. | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: she:Shewmr4_2901 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | 0.547 |
Spea_0968 | Spea_0969 | Spea_0968 | Spea_0969 | KEGG: slo:Shew_1005 rRNA (guanine-N(1)-)-methyltransferase. | PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; KEGG: slo:Shew_1006 ErfK/YbiS/YcfS/YnhG family protein. | 0.608 |
Spea_0968 | uppP | Spea_0968 | Spea_0967 | KEGG: slo:Shew_1005 rRNA (guanine-N(1)-)-methyltransferase. | Putative undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.609 |
Spea_0969 | Spea_0965 | Spea_0969 | Spea_0965 | PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; KEGG: slo:Shew_1006 ErfK/YbiS/YcfS/YnhG family protein. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.440 |
Spea_0969 | Spea_0966 | Spea_0969 | Spea_0966 | PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; KEGG: slo:Shew_1006 ErfK/YbiS/YcfS/YnhG family protein. | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: she:Shewmr4_2901 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | 0.443 |
Spea_0969 | Spea_0968 | Spea_0969 | Spea_0968 | PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; KEGG: slo:Shew_1006 ErfK/YbiS/YcfS/YnhG family protein. | KEGG: slo:Shew_1005 rRNA (guanine-N(1)-)-methyltransferase. | 0.608 |
Spea_0969 | uppP | Spea_0969 | Spea_0967 | PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; KEGG: slo:Shew_1006 ErfK/YbiS/YcfS/YnhG family protein. | Putative undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.491 |
Spea_3788 | mraY | Spea_3788 | Spea_3814 | PFAM: phosphoesterase PA-phosphatase related; KEGG: shn:Shewana3_3721 phosphoesterase, PA-phosphatase related. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.918 |
Spea_3788 | uppP | Spea_3788 | Spea_0967 | PFAM: phosphoesterase PA-phosphatase related; KEGG: shn:Shewana3_3721 phosphoesterase, PA-phosphatase related. | Putative undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.912 |
Spea_3788 | uppS | Spea_3788 | Spea_2881 | PFAM: phosphoesterase PA-phosphatase related; KEGG: shn:Shewana3_3721 phosphoesterase, PA-phosphatase related. | Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.920 |
glmU | murA | Spea_4237 | Spea_3603 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.955 |