STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)    
Predicted Functional Partners:
Spea_1668
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
 
 
 0.999
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.932
Spea_2795
PFAM: AMP-dependent synthetase and ligase; KEGG: sbm:Shew185_2844 AMP-dependent synthetase and ligase.
   
 
 0.932
Spea_1541
PFAM: acylphosphatase; KEGG: saz:Sama_1328 acylphosphatase.
     
 0.917
Spea_3942
PFAM: aldehyde dehydrogenase; KEGG: shm:Shewmr7_3772 aldehyde dehydrogenase (NAD(+)); Belongs to the aldehyde dehydrogenase family.
  
 
 0.917
Spea_1076
Phosphoketolase; PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: slo:Shew_1091 phosphoketolase.
  
 0.900
Spea_2041
PFAM: isocitrate lyase and phosphorylmutase; KEGG: sfr:Sfri_3139 isocitrate lyase and phosphorylmutase.
   
  
 0.884
Spea_2998
PFAM: protein of unknown function DUF162; KEGG: shm:Shewmr7_2816 protein of unknown function DUF162.
  
  
 0.713
Spea_1290
KEGG: slo:Shew_1275 malate synthase A; TIGRFAM: malate synthase A; PFAM: malate synthase.
   
  
 0.689
Spea_2005
KEGG: sbm:Shew185_4295 malate synthase.
   
  
 0.688
Your Current Organism:
Shewanella pealeana
NCBI taxonomy Id: 398579
Other names: S. pealeana ATCC 700345, Shewanella pealeana ATCC 700345, Shewanella pealeana str. ATCC 700345, Shewanella pealeana strain ATCC 700345
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