node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Spea_0350 | Spea_0421 | Spea_0350 | Spea_0421 | Serine--pyruvate transaminase; PFAM: aminotransferase class V; KEGG: son:SO_4343 aminotransferase, class V. | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | 0.904 |
Spea_0350 | Spea_1013 | Spea_0350 | Spea_1013 | Serine--pyruvate transaminase; PFAM: aminotransferase class V; KEGG: son:SO_4343 aminotransferase, class V. | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: slo:Shew_1032 glutamate synthase (ferredoxin). | 0.528 |
Spea_0350 | Spea_1142 | Spea_0350 | Spea_1142 | Serine--pyruvate transaminase; PFAM: aminotransferase class V; KEGG: son:SO_4343 aminotransferase, class V. | Threonine aldolase; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: sbm:Shew185_3026 threonine aldolase. | 0.921 |
Spea_0350 | Spea_2205 | Spea_0350 | Spea_2205 | Serine--pyruvate transaminase; PFAM: aminotransferase class V; KEGG: son:SO_4343 aminotransferase, class V. | Threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: gme:Gmet_0270 aromatic amino acid beta-eliminating lyase/threonine aldolase. | 0.921 |
Spea_0350 | gcvH | Spea_0350 | Spea_3302 | Serine--pyruvate transaminase; PFAM: aminotransferase class V; KEGG: son:SO_4343 aminotransferase, class V. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.920 |
Spea_0350 | gcvP | Spea_0350 | Spea_3301 | Serine--pyruvate transaminase; PFAM: aminotransferase class V; KEGG: son:SO_4343 aminotransferase, class V. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.942 |
Spea_0350 | gcvT | Spea_0350 | Spea_3303 | Serine--pyruvate transaminase; PFAM: aminotransferase class V; KEGG: son:SO_4343 aminotransferase, class V. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.940 |
Spea_0350 | glyA | Spea_0350 | Spea_1160 | Serine--pyruvate transaminase; PFAM: aminotransferase class V; KEGG: son:SO_4343 aminotransferase, class V. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.941 |
Spea_0350 | kbl | Spea_0350 | Spea_0107 | Serine--pyruvate transaminase; PFAM: aminotransferase class V; KEGG: son:SO_4343 aminotransferase, class V. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.918 |
Spea_0421 | Spea_0350 | Spea_0421 | Spea_0350 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | Serine--pyruvate transaminase; PFAM: aminotransferase class V; KEGG: son:SO_4343 aminotransferase, class V. | 0.904 |
Spea_0421 | Spea_1013 | Spea_0421 | Spea_1013 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: slo:Shew_1032 glutamate synthase (ferredoxin). | 0.879 |
Spea_0421 | Spea_2038 | Spea_0421 | Spea_2038 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.409 |
Spea_0421 | gcvH | Spea_0421 | Spea_3302 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.970 |
Spea_0421 | gcvP | Spea_0421 | Spea_3301 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.948 |
Spea_0421 | gcvT | Spea_0421 | Spea_3303 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.958 |
Spea_0421 | glyA | Spea_0421 | Spea_1160 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.929 |
Spea_1013 | Spea_0350 | Spea_1013 | Spea_0350 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: slo:Shew_1032 glutamate synthase (ferredoxin). | Serine--pyruvate transaminase; PFAM: aminotransferase class V; KEGG: son:SO_4343 aminotransferase, class V. | 0.528 |
Spea_1013 | Spea_0421 | Spea_1013 | Spea_0421 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: slo:Shew_1032 glutamate synthase (ferredoxin). | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | 0.879 |
Spea_1013 | gcvH | Spea_1013 | Spea_3302 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: slo:Shew_1032 glutamate synthase (ferredoxin). | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.876 |
Spea_1013 | gcvP | Spea_1013 | Spea_3301 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: slo:Shew_1032 glutamate synthase (ferredoxin). | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.941 |