STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fixNTIGRFAM: cytochrome c oxidase, cbb3-type, subunit I PFAM: cytochrome c oxidase subunit I; NCBI conserved domains: cd01661, cbb3_Oxidase_I; high swissprot hit to Cytochrome c oxidase subunit 1 homolog, bacteroid from Sinorhizobium meliloti; high Ref ZP hit to cytochrome c oxidase, cbb3-type, subunit I [Roseovarius sp. TM1035]; cbb3-type, subunit I; Belongs to the heme-copper respiratory oxidase family. (533 aa)    
Predicted Functional Partners:
fixO
TIGRFAM: cytochrome c oxidase, cbb3-type, subunit II PFAM: cytochrome C oxidase mono-heme subunit/FixO; NCBI conserved domains: fixO; no significant swissprot, high Ref ZP hit to cytochrome c oxidase, cbb3-type, subunit II [Roseovarius sp. TM1035]; cbb3-type, subunit II.
 0.999
fixQ
PFAM: Cbb3-type cytochrome oxidase component; NCBI conserved domains: fixQ; no significant swissprot hit; low Ref ZP hit to cytochrome c oxidase, cbb3-type, subunit IV [Loktanella vestfoldensis SKA53]; cbb3-type, subunit IV.
  
 
 0.999
fixP
Cytochrome c oxidase; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
 
 0.999
Dshi_1660
Transcriptional regulator; TIGRFAM: TIGR00738; PFAM: PF02082; SUPERFAMILY: SSF46785.
  
  
 0.999
fixG
Nitrogen fixation protein fixG; TIGRFAM: Cytochrome c oxidase cbb3 type accessory protein FixG; PFAM00037 4Fe-4S binding domain; high swissprot hit to Nitrogen fixation protein fixG from Sinorhizobium meliloti; high Ref ZP hit to iron-sulfur-binding protein, RdxA/RdxB/FixG family [Roseobacter sp. AzwK-3b].
 
  
 0.995
fixH
PFAM: FixH family protein; NCBI conserved domains: fixH; low swissprot hit to Nitrogen fixation protein fixH from Sinorhizobium meliloti, middle Ref ZP hit to FixH [Silicibacter sp. TM1040].
 
 
 0.992
hemN2
TIGRFAM: oxygen-independent coproporphyrinogen III oxidase PFAM: Radical SAM domain protein; HemN domain protein (same as NCBI conserved domains); high swissprot hit to Oxygen-independent coproporphyrinogen III oxidase from Paracoccus denitrificans PD1222; high Ref ZP hit to coproporphyrinogen III oxidase [Roseovarius sp. TM1035]; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
 
  
 0.981
petB
Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  
 0.939
ctaC
Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
    
 0.928
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
    
 0.919
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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