STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dshi_1048Enoyl-CoA hydratase and 3-2trans-enoyl-CoA isomerase are two enzymes involved in fatty acid metabolism; Belongs to the enoyl-CoA hydratase/isomerase family. (265 aa)    
Predicted Functional Partners:
hbdA
PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding KEGG: sil:SPO0717 3-hydroxybutyryl-CoA dehydrogenase; high swissprot, good RBS site AGGAT.
 
 0.975
Dshi_1049
Short-chain dehydrogenase/reductase SDR; Large family of oxidoreductases; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 0.847
Dshi_1047
Conserved hypothetical protein.
  
    0.836
Dshi_1893
LOV-regulator, Blue-light sensing; Similar to to known LOV domains (e.g SB1 and SB2 from Pseudomonas putida); highly conserved LOV consensus region including the photoactive Cys. TIGRFAM: TIGR00229 PAS domain S-box; COG: COG0642 - Signal transduction histidine kinase; SMART: SM00091: PAS domain; SM00086: PAC motif, SM00388: Histidine kinase-like ATPases, SM00448 : cheY-homologous receiver domain; PROSITE: PS50112: PAS repeat profile, PS50113: PAC domain profile, PS50110: Response regulatory domain profile, PS50109: Histidine kinase domain profile; PFAM: PF00072: Response regulator rece [...]
   
 
 0.802
Dshi_3346
KEGG: sil:SPO0094 sensory box sensor histidine kinase/response regulator TIGRFAM: PAS sensor protein PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein SMART: PAS domain containing protein; PAC repeat-containing protein.
   
 
 0.799
Dshi_2676
Histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein.
   
 
 0.789
Dshi_2708
Sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein SMART: PAS domain containing protein.
   
 
 0.789
Dshi_3332
Sensor histidine kinase/response regulator; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein KEGG: rde:RD1_0357 hybrid sensory histidine kinase, putative.
   
 
 0.789
Dshi_1051
MmgE/PrpD family protein; This family includes 2-methylcitrate dehydratase (PrpD) that is required for propionate catabolism. It catalyses the third step of the 2-methylcitric acid cycle.
  
    0.785
Dshi_1050
Conserved hypothetical protein.
  
    0.775
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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