STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dshi_1676HAD-like hydrolase; TIGRFAMS: TIGR01509 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; COG: COG0637 - Predicted phosphatase/phosphohexomutase; PFAM: PF00702; SPRINT: PR00413; PROSITE: PS01228; SWISSPROT Q9X0Y1: Phosphorylated carbohydrates phosphatase TM_1254, P77475: Phosphatase yqaB. (219 aa)    
Predicted Functional Partners:
Dshi_1675
Hypothetical protein; COG:COG0685, Gene3D: G3DSA:3.20.20.220.
  
    0.866
Dshi_1677
Putative dehypteroate synthase; COG: COG1410 - Methionine synthase I, cobalamin-binding domain; SUPERFAMILY SSF51717 & Gene3D G3DSA:3.20.20.20: Dihydropteroate synthetase-like; PFAM: PF00809; PROSITE: PS50972.
       0.815
Dshi_1674
Conserved hypothetical protein.
  
    0.759
Dshi_1678
Conserved hypothetical protein.
  
    0.589
gph-2
Putative phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
 
  
 0.558
Dshi_2818
HAD-like hydrolase; Swiss-Prot: P32662-Phosphoglycolate phosphatase TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1 PFAM: Haloacid dehalogenase domain protein hydrolase.
  
  
 0.493
Dshi_1295
HAD-superfamily hydrolase; Specifically catalyzes the dephosphorylation of 2-phosphoglycolate; subfamily IA, variant 3.
 
  
0.455
Dshi_1935
COG: COG0492 - Thioredoxin reductase; PFAM: PF00027, PF00070; PROSITE: PS50042; SMART: SM00100; PRINTS: PR00469, PR00419, PR00368.
 
  
 0.452
Dshi_1673
Phosphatase; COG: COG0248 - Exopolyphosphatase; SWISSPROT P25552: Guanosine-5-triphosphate,3-diphosphate pyrophosphatase; PFAM: PF02541; Gene3D: G3DSA:3.30.420.150, G3DSA:3.30.420.40; SUPERFAMILY: SSF53067.
     
 0.421
Dshi_0219
KEGG: rsq:Rsph17025_2554 hypothetical protein; no significant swissprot; no conserved domains.
  
    0.412
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.