STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Dshi_2357COG1960: Acyl-CoA dehydrogenases PFAM: Acyl-CoA dehydrogenase. (406 aa)    
Predicted Functional Partners:
fadJ
3-hydroxyacyl-CoA dehydrogenase NAD-binding; Multifunctional enzyme: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase, Reaction: (3S)-3-Hydroxyacyl-CoA <=> trans-2,3-Dehydroacyl-CoA + H2O, Reaction: (S)-3-hydroxybutanoyl-CoA = (R)-3-hydroxybutanoyl-CoA; 3-hydroxyacyl-CoA dehydrogenase, Reaction(EC:1.1.1.35):(3S)-3-Hydroxyacyl-CoA + NAD+ <=> 3-Oxoacyl-CoA + NADH + H+.
 
 0.985
lpdA
SWISSPROT P0A9P0: Dihydrolipoyl dehydrogenase; PFAM: PF00364, PF00070, PF02852, PF07992; PROSITE: PS50968, PS00189, PS00076; PRINTS: PR00945, PR00411, PR00368; TIGRFAM: TIGR01350 dihydrolipoamide dehydrogenase; COG: COG1249 - Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
  
 0.921
Dshi_0838
Contains all Acyl-CoA dehydrogenase domains; Reaction: Acyl-CoA + Acceptor <=> 2,3-Dehydroacyl-CoA + Reduced acceptor.
  
  
 
0.918
eftA
PFAM: Electron transfer flavoprotein alpha/beta-subunit; Electron transfer flavoprotein alpha subunit KEGG: rde:RD1_1387 electron transfer flavoprotein, alpha subunit, high swissprot.
 
 0.916
Dshi_1004
acyl-CoA dehydrogenase domain protein; Contains middle and C-terminal domain, N-terminal domain not conserved.
  
 
 
0.913
lpdV
SWISSPROT Q9I1L9: Dihydrolipoyl dehydrogenase; TIGRFAM: TIGR01350; PFAM: PF00070, PF02852, PF07992.
   
 0.909
sucB
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
   
 0.909
lpd
SWISSPROT P14218: Dihydrolipoyl dehydrogenase; TIGRFAM: TIGR01350 dihydrolipoamide dehydrogenase; COG: COG1249 - Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; PFAM: PF00070, PF02852, PF07992; PRINTS: PR00945, PR00411, PR00368.
   
 0.909
Dshi_1058
acyl-CoA dehydrogenase domain protein; N-terminal, middle and C-terminal domain, Oxidoreductase acting on the CH-CH group of donors with other acceptors.
  
 
 
0.908
hbdA
PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding KEGG: sil:SPO0717 3-hydroxybutyryl-CoA dehydrogenase; high swissprot, good RBS site AGGAT.
 
 0.815
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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