STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureCSwiss-Prot: Q28RJ3-Urease subunit alpha ureC TIGRFAM: urease, alpha subunit PFAM: amidohydrolase; Urease alpha-subunit domain protein; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (569 aa)    
Predicted Functional Partners:
ureB
Swiss-Prot: Q28RJ8-Urease subunit beta ureB TIGRFAM: urease, beta subunit PFAM: Urease beta subunit; Belongs to the urease beta subunit family.
 0.999
ureA
Swiss-Prot: Q9RFF5-Urease subunit gamma ureA TIGRFAM: urease, gamma subunit PFAM: Urease gamma subunit region; Belongs to the urease gamma subunit family.
 0.999
ureG
Urease accessory protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
  
 0.994
ureF
Putative urease accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.992
ureD
Urease accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
  
 0.962
ureE
Urease accessory domain protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.957
Dshi_2309
Arginase; Swiss-Prot: P39138-Arginase TIGRFAM: arginase PFAM: Arginase/agmatinase/formiminoglutamase COG0010: Arginase/agmatinase/formimionoglutamate hydrolase, arginase family KEGG: rde:RD1_1416 arginase; Belongs to the arginase family.
    
  0.904
allA
Ureidoglycolatehydrolase; PFAM: Ureidoglycolate hydrolase KEGG: rsh:Rsph17029_0204 ureidoglycolate hydrolase.
  
 
  0.902
Dshi_2366
Hypothetical protein.
  
    0.617
gltB
Glutamate synthase; PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase KEGG: sit:TM1040_2823 glutamate synthase (ferredoxin), involved in nitrogen metabolism PATH: rn00910.
   
  
 0.451
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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