STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dshi_2763Hypothetical protein; Swiss-Prot: P09983-Hemolysin, chromosomal PFAM: Hemolysin-type calcium-binding region; related to hemolysin. (554 aa)    
Predicted Functional Partners:
Dshi_1397
Contains several Hemolysin-type calcium-binding repeats found in proteins that are secreted into the growth medium by a mechanism that does not require a cleaved N-terminal signal sequence.
  
  
 0.778
Dshi_1622
SWISSPROT Q99289: Thermolabile hemolysin [Precursor]; PFAM: PF00353; PROSITE: PS00330; SPRINT: PR00313; SUPERFAMILY: SSF51120; Gene3D: G3DSA:2.150.10.10; COG: COG2931; Calcium binding.
  
   
 0.776
Dshi_2425
Hypothetical protein; PFAM: Hemolysin-type calcium-binding region.
  
     0.749
Dshi_1895
Hypothetical protein; PFAM: PF00353.
  
     0.746
Dshi_3402
KEGG: rsp:RSP_0230 neutral zinc metallopeptidase CD: Zinc-dependent metalloprotease, serralysin_like subfamily.
  
     0.656
fas
PFAM: beta-Ig-H3/fasciclin; Hemolysin-type calcium-binding region KEGG: pde:Pden_0560 hemolysin-type calcium-binding region; NCBI conserved domains: Fasciclin; middle Ref YP hit to Beta-Ig-H3/fasciclin from Ralstonia eutropha JMP134; no significant swissprot.
  
     0.583
hlyD
TIGRFAM: type I secretion membrane fusion protein, HlyD family PFAM: secretion protein HlyD family protein KEGG: sil:SPO3729 type I secretion membrane fusion protein, HlyD family; also middle swissprot hit to Proteases secretion protein prtE from Erwinia chrysanthemi; HlyD family.
 
    0.542
Dshi_2501
ABC transporter; Swiss-Prot: P18770-Cyclolysin secretion/processing ATP-binding protein cyaB; P26760-Toxin RTX-I translocation ATP-binding protein PFAM: ABC transporter transmembrane region; ABC transporter related SMART: AAA ATPase KEGG: rde:RD1_1124 toxin secretion ABC transporter, ATP-binding component, putative; colocated with secretion protein (HylD family); associated with toxin excretion.
 
  
 0.524
Dshi_2502
Secretion protein; Swiss-Prot: Q03025-Alkaline protease secretion protein aprE TIGRFAM: type I secretion membrane fusion protein, HlyD family PFAM: secretion protein HlyD family protein KEGG: rde:RD1_1123 HlyD family secretion protein, putative; colocated with ABC transporter; HlyD family.
 
    0.523
Dshi_2764
Hypothetical protein.
       0.507
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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