STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
deoDSwiss-Prot: P0ABP8-Purine nucleoside phosphorylase deoD-type TIGRFAM: purine nucleoside phosphorylase PFAM: purine or other phosphorylase family 1. (234 aa)    
Predicted Functional Partners:
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
 
 0.973
deoA
Pyrimidine-nucleoside phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
 
 
 0.964
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
 
 
 0.957
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.934
tdk
Swiss-Prot: Q5LUY8-Thymidine kinase PFAM: thymidine kinase.
  
 
 0.931
npdA
Swiss-Prot: P75960- NAD-dependent deacetylase (Regulatory protein SIR2 homolog) KEGG: sit:TM1040_2119 hypothetical protein COG0846: NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily.
    
 0.930
hpt
SWISSPROT P0A9M2: Hypoxanthine phosphoribosyltransferase, also high similarity to hypoxanthine-guanine phosphoribosyltransferase (SWISSPROT P37171); COG: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; PFAM: PF00156; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
   
 
 0.918
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
   
 
 0.918
ade
Adenine deaminases reaction is important for adenine utilisation as a purine and also as a nitrogen source, Reaction: Adenine + H2O <=> hypoxanthine + NH3, Manganese dependent; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
   
 
 0.916
add
Adenosine deaminase; Acting on carbon-nitrogen bonds, other than peptide bonds, Reaction: Adenosine + H2O <=> Inosine + NH3.
  
 
 0.914
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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