STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argGTIGRFAM: argininosuccinate synthase PFAM: argininosuccinate synthase KEGG: rde:RD1_0417 argininosuccinate synthase; Citrulline--aspartate ligase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (406 aa)    
Predicted Functional Partners:
argH
TIGRFAM: argininosuccinate lyase PFAM: fumarate lyase KEGG: sil:SPO0332 argininosuccinate lyase.
 
 0.998
carB
Swiss-Prot: P00968-Carbamoyl-phosphate synthase large chain TIGRFAM: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family.
 
 
 0.997
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
 
 
 0.989
arcB
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
  
 
 0.982
argD
Pyridoxalphosphate-dependent aminotransferase classIII, Reaction: N-Acetylornithine + 2-Oxoglutarate <=> N-Acetyl-L-glutamate-5-semialdehyde + L-glutamate; N2-Succinyl-L-ornithine + 2-Oxoglutarate <=> N-Succinyl-L-glutamate-5-semialdehyde + L-Glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
 
 0.942
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.938
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 
  
 0.935
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
 
  
 0.932
carA
Swiss-Prot: Q92N95-Carbamoyl-phosphate synthase small chain carA TIGRFAM: carbamoyl-phosphate synthase, small subunit PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; small chain; Belongs to the CarA family.
  
 
 0.930
aspC
Contains Aminotransferase class I and II domain.
  
 0.925
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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