STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dshi_3485PFAM: response regulator receiver; Stage II sporulation E family protein SMART: protein phosphatase 2C domain protein KEGG: rde:RD1_0413 response regulator. (422 aa)    
Predicted Functional Partners:
rsbW
KEGG: rde:RD1_0027 serine-protein kinase, putative; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); ATP-binding region is related to ATPase domains of histidine kinase; Anti-sigma-B factor.
 
 
 0.999
Dshi_2815
Conserved hypothetical protein; PFAM: Heme NO binding domain protein.
  
  
 0.999
Dshi_3363
Putative flagellar protein FlgJ; PRK: flgJ, peptidoglycan hydrolase KEGG: sit:TM1040_2976 flagellar protein FlgJ, putative.
   
    0.999
Dshi_3402
KEGG: rsp:RSP_0230 neutral zinc metallopeptidase CD: Zinc-dependent metalloprotease, serralysin_like subfamily.
   
  
 0.999
Dshi_0073
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor PFAM: Sulfate transporter/antisigma-factor antagonist STAS KEGG: rsq:Rsph17025_2906 anti-sigma-factor antagonist, SpoIIAA domain: The establishment of differential gene expression in sporulating Bacillus subtilis involves four protein components one of which is SpoIIAA (). The four components regulate the sporulation sigma factor F. Early in sporulation, SpoIIAA is in the phosphorylated state (SpoIIAA-P), as a result.
 
 
 0.998
Dshi_3484
PFAM: Hpt domain protein KEGG: sit:TM1040_2886 Hpt protein.
 
 
 0.997
Dshi_3346
KEGG: sil:SPO0094 sensory box sensor histidine kinase/response regulator TIGRFAM: PAS sensor protein PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein SMART: PAS domain containing protein; PAC repeat-containing protein.
 
0.975
Dshi_1893
LOV-regulator, Blue-light sensing; Similar to to known LOV domains (e.g SB1 and SB2 from Pseudomonas putida); highly conserved LOV consensus region including the photoactive Cys. TIGRFAM: TIGR00229 PAS domain S-box; COG: COG0642 - Signal transduction histidine kinase; SMART: SM00091: PAS domain; SM00086: PAC motif, SM00388: Histidine kinase-like ATPases, SM00448 : cheY-homologous receiver domain; PROSITE: PS50112: PAS repeat profile, PS50113: PAC domain profile, PS50110: Response regulatory domain profile, PS50109: Histidine kinase domain profile; PFAM: PF00072: Response regulator rece [...]
 
 
 0.968
Dshi_0824
Histidine kinase; C-Terminal domain of arcB (aerobic respiration control), no PAS domain (sensor).
 
 0.965
Dshi_3332
Sensor histidine kinase/response regulator; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein KEGG: rde:RD1_0357 hybrid sensory histidine kinase, putative.
 
 
0.955
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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