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glyA protein (Geobacter lovleyi) - STRING interaction network
"glyA" - Serine hydroxymethyltransferase in Geobacter lovleyi
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (415 aa)    
Predicted Functional Partners:
Glov_2675
TIGRFAM- glycine cleavage system T protein; PFAM- glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG- gme-Gmet_3155 glycine cleavage system T protein (366 aa)
 
  0.996
folD
Bifunctional protein FolD; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (284 aa)
 
 
  0.994
Glov_2671
PFAM- glycine cleavage system P-protein; KEGG- gme-Gmet_3152 glycine dehydrogenase subunit 2 (481 aa)
 
 
  0.986
purH
Bifunctional purine biosynthesis protein PurH; KEGG- gsu-GSU0609 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM- phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM- MGS domain protein; AICARFT/IMPCHase bienzyme formylation region (519 aa)
   
  0.984
Glov_0070
Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM- AICARFT/IMPCHase bienzyme formylation region; KEGG- cac-CAC2445 5-aminoimidazole-4-carboxamide ribonucleotide transformylase (388 aa)
   
  0.984
Glov_1933
KEGG- ppd-Ppro_1747 sugar-phosphate isomerases, RpiB/LacA/LacB family; TIGRFAM- sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM- Ribose/galactose isomerase (149 aa)
   
 
  0.984
Glov_3721
PFAM- Methionine synthase vitamin-B12 independent; KEGG- sgr-SGR_5029 putative 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase (365 aa)
   
 
  0.981
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate (206 aa)
 
 
  0.974
gcvPA
Probable glycine dehydrogenase (decarboxylating) subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (448 aa)
 
 
  0.971
Glov_3333
L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde (347 aa)
     
  0.970
Your Current Organism:
Geobacter lovleyi
NCBI taxonomy Id: 398767
Other names: G. lovleyi SZ, Geobacter lovleyi, Geobacter lovleyi SZ, Geobacter lovleyi str. SZ, Geobacter lovleyi strain SZ
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