node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Glov_0185 | clpB | Glov_0185 | Glov_1996 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gsu:GSU2406 DnaJ domain protein. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.834 |
Glov_0185 | dnaK | Glov_0185 | Glov_2829 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gsu:GSU2406 DnaJ domain protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.998 |
Glov_0185 | ftsH | Glov_0185 | Glov_2522 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gsu:GSU2406 DnaJ domain protein. | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.629 |
Glov_0185 | groL | Glov_0185 | Glov_2929 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gsu:GSU2406 DnaJ domain protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.855 |
Glov_0185 | grpE | Glov_0185 | Glov_2830 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gsu:GSU2406 DnaJ domain protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.947 |
Glov_0185 | lon-2 | Glov_0185 | Glov_2806 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gsu:GSU2406 DnaJ domain protein. | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.710 |
Glov_2803 | Glov_2804 | Glov_2803 | Glov_2804 | Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: ppd:Ppro_2600 transcriptional regulator, Crp/Fnr family. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.778 |
Glov_2803 | Glov_2807 | Glov_2803 | Glov_2807 | Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: ppd:Ppro_2600 transcriptional regulator, Crp/Fnr family. | PFAM: heat shock protein Hsp20; KEGG: ppd:Ppro_2605 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. | 0.724 |
Glov_2803 | lon-2 | Glov_2803 | Glov_2806 | Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: ppd:Ppro_2600 transcriptional regulator, Crp/Fnr family. | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.707 |
Glov_2803 | thiL | Glov_2803 | Glov_2805 | Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: ppd:Ppro_2600 transcriptional regulator, Crp/Fnr family. | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.702 |
Glov_2804 | Glov_2803 | Glov_2804 | Glov_2803 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: ppd:Ppro_2600 transcriptional regulator, Crp/Fnr family. | 0.778 |
Glov_2804 | Glov_2807 | Glov_2804 | Glov_2807 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | PFAM: heat shock protein Hsp20; KEGG: ppd:Ppro_2605 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. | 0.753 |
Glov_2804 | lon-2 | Glov_2804 | Glov_2806 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.708 |
Glov_2804 | thiL | Glov_2804 | Glov_2805 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.736 |
Glov_2807 | Glov_2803 | Glov_2807 | Glov_2803 | PFAM: heat shock protein Hsp20; KEGG: ppd:Ppro_2605 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. | Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: ppd:Ppro_2600 transcriptional regulator, Crp/Fnr family. | 0.724 |
Glov_2807 | Glov_2804 | Glov_2807 | Glov_2804 | PFAM: heat shock protein Hsp20; KEGG: ppd:Ppro_2605 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.753 |
Glov_2807 | clpB | Glov_2807 | Glov_1996 | PFAM: heat shock protein Hsp20; KEGG: ppd:Ppro_2605 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.722 |
Glov_2807 | dnaK | Glov_2807 | Glov_2829 | PFAM: heat shock protein Hsp20; KEGG: ppd:Ppro_2605 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.559 |
Glov_2807 | grpE | Glov_2807 | Glov_2830 | PFAM: heat shock protein Hsp20; KEGG: ppd:Ppro_2605 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.530 |
Glov_2807 | lon-2 | Glov_2807 | Glov_2806 | PFAM: heat shock protein Hsp20; KEGG: ppd:Ppro_2605 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.842 |