node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Glov_0185 | Glov_1079 | Glov_0185 | Glov_1079 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gsu:GSU2406 DnaJ domain protein. | KEGG: ppd:Ppro_2145 molecular chaperone-like protein. | 0.992 |
Glov_0185 | clpB | Glov_0185 | Glov_1996 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gsu:GSU2406 DnaJ domain protein. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.834 |
Glov_0185 | clpP | Glov_0185 | Glov_1928 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gsu:GSU2406 DnaJ domain protein. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.490 |
Glov_0185 | dnaK | Glov_0185 | Glov_2829 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gsu:GSU2406 DnaJ domain protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.998 |
Glov_0185 | groL | Glov_0185 | Glov_2929 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gsu:GSU2406 DnaJ domain protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.855 |
Glov_0185 | groS | Glov_0185 | Glov_2928 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gsu:GSU2406 DnaJ domain protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.756 |
Glov_0185 | grpE | Glov_0185 | Glov_2830 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gsu:GSU2406 DnaJ domain protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.947 |
Glov_0185 | htpG | Glov_0185 | Glov_2143 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gsu:GSU2406 DnaJ domain protein. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.944 |
Glov_1079 | Glov_0185 | Glov_1079 | Glov_0185 | KEGG: ppd:Ppro_2145 molecular chaperone-like protein. | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gsu:GSU2406 DnaJ domain protein. | 0.992 |
Glov_1079 | clpB | Glov_1079 | Glov_1996 | KEGG: ppd:Ppro_2145 molecular chaperone-like protein. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.968 |
Glov_1079 | clpP | Glov_1079 | Glov_1928 | KEGG: ppd:Ppro_2145 molecular chaperone-like protein. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.715 |
Glov_1079 | dnaJ | Glov_1079 | Glov_2828 | KEGG: ppd:Ppro_2145 molecular chaperone-like protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.933 |
Glov_1079 | groL | Glov_1079 | Glov_2929 | KEGG: ppd:Ppro_2145 molecular chaperone-like protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.946 |
Glov_1079 | groS | Glov_1079 | Glov_2928 | KEGG: ppd:Ppro_2145 molecular chaperone-like protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.876 |
Glov_1079 | grpE | Glov_1079 | Glov_2830 | KEGG: ppd:Ppro_2145 molecular chaperone-like protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.976 |
Glov_1079 | htpG | Glov_1079 | Glov_2143 | KEGG: ppd:Ppro_2145 molecular chaperone-like protein. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.989 |
clpB | Glov_0185 | Glov_1996 | Glov_0185 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: gsu:GSU2406 DnaJ domain protein. | 0.834 |
clpB | Glov_1079 | Glov_1996 | Glov_1079 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | KEGG: ppd:Ppro_2145 molecular chaperone-like protein. | 0.968 |
clpB | clpP | Glov_1996 | Glov_1928 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.971 |
clpB | dnaJ | Glov_1996 | Glov_2828 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.783 |