node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Glov_0070 | Glov_1031 | Glov_0070 | Glov_1031 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: AICARFT/IMPCHase bienzyme formylation region; KEGG: cac:CAC2445 5-aminoimidazole-4-carboxamide ribonucleotide transformylase. | PFAM: phosphoribosyltransferase; KEGG: azo:azo3670 hypoxanthine-guanine phosphoribosyltransferase. | 0.921 |
Glov_0070 | Glov_2695 | Glov_0070 | Glov_2695 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: AICARFT/IMPCHase bienzyme formylation region; KEGG: cac:CAC2445 5-aminoimidazole-4-carboxamide ribonucleotide transformylase. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: ppd:Ppro_1145 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.984 |
Glov_0070 | guaB | Glov_0070 | Glov_1900 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: AICARFT/IMPCHase bienzyme formylation region; KEGG: cac:CAC2445 5-aminoimidazole-4-carboxamide ribonucleotide transformylase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.959 |
Glov_0070 | purA | Glov_0070 | Glov_3251 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: AICARFT/IMPCHase bienzyme formylation region; KEGG: cac:CAC2445 5-aminoimidazole-4-carboxamide ribonucleotide transformylase. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.971 |
Glov_0070 | purH | Glov_0070 | Glov_2760 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: AICARFT/IMPCHase bienzyme formylation region; KEGG: cac:CAC2445 5-aminoimidazole-4-carboxamide ribonucleotide transformylase. | KEGG: gsu:GSU0609 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.904 |
Glov_0070 | purL | Glov_0070 | Glov_2699 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: AICARFT/IMPCHase bienzyme formylation region; KEGG: cac:CAC2445 5-aminoimidazole-4-carboxamide ribonucleotide transformylase. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.980 |
Glov_1031 | Glov_0070 | Glov_1031 | Glov_0070 | PFAM: phosphoribosyltransferase; KEGG: azo:azo3670 hypoxanthine-guanine phosphoribosyltransferase. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: AICARFT/IMPCHase bienzyme formylation region; KEGG: cac:CAC2445 5-aminoimidazole-4-carboxamide ribonucleotide transformylase. | 0.921 |
Glov_1031 | guaB | Glov_1031 | Glov_1900 | PFAM: phosphoribosyltransferase; KEGG: azo:azo3670 hypoxanthine-guanine phosphoribosyltransferase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.931 |
Glov_1031 | purA | Glov_1031 | Glov_3251 | PFAM: phosphoribosyltransferase; KEGG: azo:azo3670 hypoxanthine-guanine phosphoribosyltransferase. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.941 |
Glov_1031 | purH | Glov_1031 | Glov_2760 | PFAM: phosphoribosyltransferase; KEGG: azo:azo3670 hypoxanthine-guanine phosphoribosyltransferase. | KEGG: gsu:GSU0609 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.921 |
Glov_1031 | purL | Glov_1031 | Glov_2699 | PFAM: phosphoribosyltransferase; KEGG: azo:azo3670 hypoxanthine-guanine phosphoribosyltransferase. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.506 |
Glov_1501 | Glov_1768 | Glov_1501 | Glov_1768 | KEGG: aav:Aave_0959 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase. | PFAM: aminotransferase class I and II; KEGG: gsu:GSU1242 aspartate aminotransferase. | 0.917 |
Glov_1501 | argG | Glov_1501 | Glov_3148 | KEGG: aav:Aave_0959 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase. | PFAM: argininosuccinate synthase; KEGG: gsu:GSU0153 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.925 |
Glov_1501 | purA | Glov_1501 | Glov_3251 | KEGG: aav:Aave_0959 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.930 |
Glov_1501 | purL | Glov_1501 | Glov_2699 | KEGG: aav:Aave_0959 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.548 |
Glov_1501 | pyrB | Glov_1501 | Glov_2085 | KEGG: aav:Aave_0959 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase. | KEGG: gme:Gmet_1769 aspartate carbamoyltransferase catalytic subunit; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.925 |
Glov_1768 | Glov_1501 | Glov_1768 | Glov_1501 | PFAM: aminotransferase class I and II; KEGG: gsu:GSU1242 aspartate aminotransferase. | KEGG: aav:Aave_0959 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase. | 0.917 |
Glov_1768 | argG | Glov_1768 | Glov_3148 | PFAM: aminotransferase class I and II; KEGG: gsu:GSU1242 aspartate aminotransferase. | PFAM: argininosuccinate synthase; KEGG: gsu:GSU0153 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.925 |
Glov_1768 | purA | Glov_1768 | Glov_3251 | PFAM: aminotransferase class I and II; KEGG: gsu:GSU1242 aspartate aminotransferase. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.918 |
Glov_1768 | pyrB | Glov_1768 | Glov_2085 | PFAM: aminotransferase class I and II; KEGG: gsu:GSU1242 aspartate aminotransferase. | KEGG: gme:Gmet_1769 aspartate carbamoyltransferase catalytic subunit; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.918 |