node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Smar_1107 | csl4 | Smar_1107 | Smar_0634 | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: ape:APE0754 mitochondrial-type HSP70. | RNA binding S1 domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | 0.980 |
Smar_1107 | nep1 | Smar_1107 | Smar_1081 | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: ape:APE0754 mitochondrial-type HSP70. | Suppressor Mra1; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. | 0.999 |
Smar_1107 | rps11 | Smar_1107 | Smar_0814 | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: ape:APE0754 mitochondrial-type HSP70. | SSU ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. | 0.999 |
Smar_1107 | rps4 | Smar_1107 | Smar_0813 | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: ape:APE0754 mitochondrial-type HSP70. | SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.999 |
Smar_1107 | rps6e | Smar_1107 | Smar_0830 | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: ape:APE0754 mitochondrial-type HSP70. | PFAM: ribosomal protein S6e; KEGG: sso:SSO0411 30S ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. | 0.999 |
Smar_1107 | rrp4 | Smar_1107 | Smar_0858 | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: ape:APE0754 mitochondrial-type HSP70. | Ribosomal RNA-processing protein RRP4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. | 0.974 |
Smar_1107 | rrp41 | Smar_1107 | Smar_0859 | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: ape:APE0754 mitochondrial-type HSP70. | Ribosomal RNA-processing protein RRP41/SKI6; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. | 0.951 |
Smar_1107 | rrp42 | Smar_1107 | Smar_0860 | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: ape:APE0754 mitochondrial-type HSP70. | Ribosomal RNA-processing protein RRP42; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. | 0.970 |
Smar_1107 | rtcA | Smar_1107 | Smar_0935 | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: ape:APE0754 mitochondrial-type HSP70. | RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. | 0.951 |
Smar_1107 | tmcA | Smar_1107 | Smar_1124 | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: ape:APE0754 mitochondrial-type HSP70. | Protein of unknown function DUF699, ATPase putative; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). | 0.999 |
csl4 | Smar_1107 | Smar_0634 | Smar_1107 | RNA binding S1 domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: ape:APE0754 mitochondrial-type HSP70. | 0.980 |
csl4 | nep1 | Smar_0634 | Smar_1081 | RNA binding S1 domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | Suppressor Mra1; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. | 0.986 |
csl4 | rps11 | Smar_0634 | Smar_0814 | RNA binding S1 domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | SSU ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. | 0.939 |
csl4 | rps4 | Smar_0634 | Smar_0813 | RNA binding S1 domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.955 |
csl4 | rps6e | Smar_0634 | Smar_0830 | RNA binding S1 domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | PFAM: ribosomal protein S6e; KEGG: sso:SSO0411 30S ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. | 0.951 |
csl4 | rrp4 | Smar_0634 | Smar_0858 | RNA binding S1 domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | Ribosomal RNA-processing protein RRP4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. | 0.999 |
csl4 | rrp41 | Smar_0634 | Smar_0859 | RNA binding S1 domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | Ribosomal RNA-processing protein RRP41/SKI6; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. | 0.999 |
csl4 | rrp42 | Smar_0634 | Smar_0860 | RNA binding S1 domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | Ribosomal RNA-processing protein RRP42; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. | 0.999 |
csl4 | rtcA | Smar_0634 | Smar_0935 | RNA binding S1 domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. | 0.970 |
csl4 | tmcA | Smar_0634 | Smar_1124 | RNA binding S1 domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | Protein of unknown function DUF699, ATPase putative; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). | 0.730 |