STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
top6ASpo11/DNA topoisomerase VI, subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (434 aa)    
Predicted Functional Partners:
top6B
DNA topoisomerase VI, B subunit; Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
 
 
 0.990
radA
DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
  
 
 
 0.715
Smar_0618
SMART: AAA ATPase; KEGG: mst:Msp_0369 RadB.
    
 
 0.663
Smar_0983
PFAM: type II secretion system protein E; SMART: AAA ATPase; KEGG: ape:APE0695 Vir B11.
 
     0.587
Smar_0077
PFAM: SMC domain protein; SMART: AAA ATPase; KEGG: mth:MTH540 intracellular protein transport protein.
    
 0.582
Smar_0016
Secreted protein; KEGG: mmp:MMP0638 hypothetical protein; contains C-terminal beta-propeller domain distantly related to WD-40 repeats.
  
 
 
 0.564
Smar_0182
ERCC4 domain protein; PFAM: helix-hairpin-helix motif; ERCC4 domain protein; KEGG: pho:PH1896m ERCC4-like helicase/ERCC4-type nuclease.
  
 
 
 0.561
Smar_0982
Hypothetical protein.
       0.527
Smar_0074
PFAM: metallophosphoesterase; KEGG: mth:MTH541 Rad32 related protein.
   
 0.523
Smar_0984
KEGG: sso:SSO0119 hypothetical protein.
       0.464
Your Current Organism:
Staphylothermus marinus
NCBI taxonomy Id: 399550
Other names: S. marinus F1, Staphylothermus marinus ATCC 43588, Staphylothermus marinus DSM 3639, Staphylothermus marinus F1, Staphylothermus marinus JCM 9404, Staphylothermus marinus str. F1, Staphylothermus marinus strain F1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.