STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rbcLRibulose-1,5-bisphosphate carboxylase/oxygenase large subunit; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. (443 aa)    
Predicted Functional Partners:
Smar_0530
Phosphatases-like protein; KEGG: chy:CHY_1358 HAD-superfamily hydrolase, subfamily IA.
    
 0.924
Smar_0798
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pto:PTO1108 phosphoglycolate phosphatase.
    
 0.914
Smar_1152
SPP-like hydrolase; Catalyzes the dephosphorylation of 2-phosphoglycolate.
    
  0.903
Smar_1357
Ribose 1,5-bisphosphate isomerase; TIGRFAM: putative translation initiation factor, aIF-2BII family; eIF-2B alpha/beta/delta-related uncharacterized proteins; PFAM: initiation factor 2B related; KEGG: tko:TK0185 translation initiation factor eIF-2B, delta subunit; Belongs to the eIF-2B alpha/beta/delta subunits family.
 
  
 0.733
Smar_1169
PFAM: class II aldolase/adducin family protein; KEGG: mta:Moth_0704 class II aldolase/adducin-like.
  
  
 0.729
Smar_0989
Translation initiation factor 2B subunit I family (IF-2BI); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
  
  
 0.613
Smar_1052
Archease family protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently.
       0.597
gap
TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: glyceraldehyde 3-phosphate dehydrogenase; dihydrodipicolinate reductase; KEGG: sto:ST1356 glyceraldehyde 3-phosphate dehydrogenase.
  
  
 0.466
Smar_1050
PFAM: phosphoesterase, PA-phosphatase related; KEGG: lbl:LBL_0992 membrane associated acid phosphatase.
       0.444
Smar_0417
KEGG: pai:PAE1774 hypothetical protein.
   
    0.433
Your Current Organism:
Staphylothermus marinus
NCBI taxonomy Id: 399550
Other names: S. marinus F1, Staphylothermus marinus ATCC 43588, Staphylothermus marinus DSM 3639, Staphylothermus marinus F1, Staphylothermus marinus JCM 9404, Staphylothermus marinus str. F1, Staphylothermus marinus strain F1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.